{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T11:25:55Z","timestamp":1740137155129,"version":"3.37.3"},"reference-count":21,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,5,18]],"date-time":"2021-05-18T00:00:00Z","timestamp":1621296000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The impact of basic atrial rhythm (sinus rhythm [SR] vs. atrial fibrillation [AF]) during AF ablation on efficacy and safety is unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>About 3375 patients from the German Ablation Registry undergoing first\u2010time AF ablation were divided according to the type of AF and the basic atrial rhythm during the ablation procedure: paroxysmal AF (PAF) and SR [group Ia], PAF and AF [group Ib]), persistent AF and SR (IIa), and persistent AF and AF (IIb).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients in SR (<jats:italic>n<\/jats:italic>\u2009=\u20092312 [67%]) underwent cryoballoon ablation more often (Ia vs. Ib <jats:italic>p<\/jats:italic>\u2009=\u2009.002 and IIa vs. IIb <jats:italic>p<\/jats:italic>\u2009=\u2009.010, whereas in patients in AF (<jats:italic>n<\/jats:italic>\u2009=\u20091063 [33%]) radiofrequency (RF)\u2010based ablation (Ia vs. Ib <jats:italic>p<\/jats:italic>\u2009=\u2009.006 and IIa vs. IIb <jats:italic>p<\/jats:italic>\u2009=\u2009.014) including left and\/or right atrial substrate modification was more frequently performed. Depending on the basic rhythm there was no difference regarding arrhythmia recurrence during long\u2010term follow\u2010up. For patients suffering from persistent AF acute procedure\u2010related complications were more often documented when ablated in AF (9.1% vs. 4.6%, <jats:italic>p<\/jats:italic>\u2009=\u2009.012). which was mainly driven by the higher occurrence of pericardial effusion\/tamponade. For patients suffering from persistent AF, favorable results were found regarding 366\u2010day Kaplan\u2013Meier estimates of the incidence of MACCE (death, myocardial infarction, and stroke; <jats:italic>p<\/jats:italic>\u2009=\u2009.011) and the composite endpoint of death, myocardial infarction, stroke, and major bleeding (<jats:italic>p<\/jats:italic>\u2009=\u2009.006), when ablated in SR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Basic atrial rhythm at the time of AF ablation did not affect long\u2010term rhythm outcome. For patients suffering from persistent AF a more favorable acute and long\u2010term safety profile was observed when ablated in SR.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.15072","type":"journal-article","created":{"date-parts":[[2021,5,6]],"date-time":"2021-05-06T17:13:47Z","timestamp":1620321227000},"page":"1833-1841","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The impact of basic atrial rhythm during catheter ablation of atrial fibrillation on clinical outcomes: Lessons from the German Ablation Registry"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1389-8564","authenticated-orcid":false,"given":"Laura","family":"Rottner","sequence":"first","affiliation":[{"name":"Department of Cardiology Universit\u00e4res Herz\u2010und Gef\u00e4\u00dfzentrum Hamburg\u2010Eppendorf  Hamburg 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Universit\u00e4tsklinikum Muenster  M\u00fcnster Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Hochadel","sequence":"additional","affiliation":[{"name":"Academic Research Organisation for Cardiovascular Medicine Institut f\u00fcr Herzinfarktforschung Ludwigshafen  Ludwigshafen am Rhein Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dietrich","family":"Andresen","sequence":"additional","affiliation":[{"name":"Department of Cardiology Evangelisches Krankenhaus Hubertus Berlin  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jochen","family":"Senges","sequence":"additional","affiliation":[{"name":"Academic Research Organisation for Cardiovascular Medicine Institut f\u00fcr Herzinfarktforschung Ludwigshafen  Ludwigshafen am Rhein Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Rillig","sequence":"additional","affiliation":[{"name":"Department of Cardiology Universit\u00e4res Herz\u2010und Gef\u00e4\u00dfzentrum Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6818-6396","authenticated-orcid":false,"given":"Andreas","family":"Metzner","sequence":"additional","affiliation":[{"name":"Department of Cardiology Universit\u00e4res Herz\u2010und Gef\u00e4\u00dfzentrum Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,5,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa612"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eus333"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.09.088"},{"issue":"7","key":"e_1_2_8_5_1","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCEP.117.005114","article-title":"Stand\u2010alone pulmonary vein isolation 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