{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T15:27:56Z","timestamp":1778945276594,"version":"3.51.4"},"reference-count":11,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,6,6]],"date-time":"2021-06-06T00:00:00Z","timestamp":1622937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Some patients have late recurrence after acutely successful radiofrequency catheter ablation (RFCA) of premature ventricular complexes (PVCs). The aim of this study was to evaluate predictors of long\u2010term success following acutely successful PVC RFCA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We identified consecutive patients at our institution with frequent PVCs undergoing RFCA and reviewed procedural data and medical records. Acute success was defined as elimination of targeted PVCs for at least 30\u2010min after RFCA. Long\u2010term success was defined as absence of targeted PVCs during all follow\u2010up visits and PVC\u2010burden &lt;5% on follow\u2010up monitoring.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 241 patients (mean age 57\u2009\u00b1\u200915 years, 58% male), 161 (66.8%) had long\u2010term success with median follow\u2010up of 17.7 (IQR, 12.2\u201329.8) months. Unadjusted predictors of late PVC recurrence were increasing age, diabetes mellitus and alcohol use, while female\u2010sex, shorter ablation\u2010time, right ventricular PVC\u2010origin, single PVC morphology, and earliest bipolar activation \u226524\u2009ms pre\u2010QRS were predictors of long\u2010term success. In multivariate\u2010analysis, female\u2010sex, single\u2010PVC morphology and earliest\u2010onset of PVC\u2009\u2265\u200924\u2009ms pre\u2010QRS were independent predictors for long\u2010term success. The positive\u2010predictive value of earliest\u2010bipolar onset of PVC\u2009\u2265\u200924\u2009ms pre\u2010QRS for long\u2010term success was 0.77 (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). Negative\u2010predictive value of PVC\u2009&lt;\u200915\u2009ms pre\u2010QRS for long\u2010term success was 0.86 (<jats:italic>p<\/jats:italic>\u2009=\u2009.003), suggesting that RFCA when the bipolar electrogram preceded QRS by &lt;15\u2009ms was unlikely to result in long\u2010term success.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Female\u2010sex, single\u2010PVC morphology, and earliest\u2010onset of bipolar electrogram \u226524\u2009ms pre\u2010QRS were multivariable predictors of long\u2010term success in patients with PVCs undergoing RFCA. RFCA at sites with local onset &lt;15\u2009ms pre\u2010QRS are unlikely to be successful.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.15114","type":"journal-article","created":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T04:59:45Z","timestamp":1622091585000},"page":"2254-2261","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Predictors of long\u2010term success after catheter ablation of premature ventricular complexes"],"prefix":"10.1111","volume":"32","author":[{"given":"Sung\u2010Il","family":"Im","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Section of Cardiac Electrophysiology University of California San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandr","family":"Voskoboinik","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Section of Cardiac Electrophysiology University of California San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0189-171X","authenticated-orcid":false,"given":"Adam","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Section of Cardiac Electrophysiology University of California San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Higuchi","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Section of Cardiac Electrophysiology University of California San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0769-8072","authenticated-orcid":false,"given":"Joshua D.","family":"Moss","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Section of Cardiac Electrophysiology University of California San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henry","family":"Hsia","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Section of Cardiac Electrophysiology University of California San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zian H.","family":"Tseng","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Section of Cardiac Electrophysiology University of California San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Randall","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Section of Cardiac Electrophysiology University of California San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory M.","family":"Marcus","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Section of Cardiac Electrophysiology University of California San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasanth","family":"Vedantham","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Section of Cardiac Electrophysiology University of California San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melvin","family":"Scheinman","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Section of Cardiac Electrophysiology University of California San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Byron","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Section of Cardiac Electrophysiology University of California San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyoung\u2010Min","family":"Park","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Heart Vascular and Stroke Institute, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7200-3521","authenticated-orcid":false,"given":"Edward P.","family":"Gerstenfeld","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Section of Cardiac Electrophysiology University of California San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,6,6]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.113.000805"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.14127"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2015.04.005"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2018.09.009"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euje.2005.12.014"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0127272"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2018.01.012"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-019-00520-3"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2011.04.026"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2003.03211.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2014.12.017"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.15114","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jce.15114","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.15114","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T17:37:13Z","timestamp":1692985033000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.15114"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,6]]},"references-count":11,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1111\/jce.15114"],"URL":"https:\/\/doi.org\/10.1111\/jce.15114","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,6]]},"assertion":[{"value":"2021-01-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}