{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T14:38:51Z","timestamp":1780324731300,"version":"3.54.1"},"reference-count":9,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,7,7]],"date-time":"2021-07-07T00:00:00Z","timestamp":1625616000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Introduction:<\/jats:bold> We aimed to determine the effects of conscious and deep sedation on vagal response (VR) characteristics during ganglionated plexus (GP) ablation. <jats:bold>Methods:<\/jats:bold> Forty consecutive patients undergoing GP ablation for vasovagal syncope were divided to receive conscious sedation with midazolam (Group 1, <jats:italic>n<\/jats:italic> = 29) or deep sedation with the midazolam\u2013propofol combination (Group 2, <jats:italic>n<\/jats:italic> = 11). VR was defined on three levels. R\u2013R interval increase of &gt;50% (Level 1); R\u2013R interval increase of 20%\u201350% (Level 2); and R\u2013R interval increase of &lt;20% (Level 3). <jats:bold>Results:<\/jats:bold> The ratio of Level 1 VR during ablation on left superior and inferior GPs was significantly lower in Group 2 (<jats:italic>p<\/jats:italic> &lt; .0001 and <jats:italic>p<\/jats:italic> = .034, respectively). Once the cut\u2010off for VR was decreased to Level 2, the ratio of (+) VR was similar between groups during ablation of left\u2010sided GPs. Positive VR in any level was lower than 20% during ablation of right\u2010sided GPs. <jats:bold>Conclusions:<\/jats:bold> The autonomic tone might be affected in different ways by the level or type of intravenous sedation. Awareness of anesthesia\u2010related differences may be important if GP ablation will be performed by using VR characteristics during ablation.<\/jats:p>","DOI":"10.1111\/jce.15133","type":"journal-article","created":{"date-parts":[[2021,6,27]],"date-time":"2021-06-27T07:29:18Z","timestamp":1624778958000},"page":"2333-2336","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Effect of conscious sedation and deep sedation on the vagal response characteristics during ganglionated plexus ablation"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8061-9660","authenticated-orcid":false,"given":"Tolga","family":"Aksu","sequence":"first","affiliation":[{"name":"Department of Cardiology Yeditepe University Hospital Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5602-0711","authenticated-orcid":false,"given":"Kivanc","family":"Yalin","sequence":"additional","affiliation":[{"name":"Department of Cardiology Istanbul\u2010Cerrahpasa University Hospital Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8677-2279","authenticated-orcid":false,"given":"Leah","family":"John","sequence":"additional","affiliation":[{"name":"Department of Cardiology Medical University of South Carolina Mt Pleasant South Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7466-123X","authenticated-orcid":false,"given":"Jose","family":"Osorio","sequence":"additional","affiliation":[{"name":"Department of Cardiology Arrhythmia Institute at Grandview Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Winterfield","sequence":"additional","affiliation":[{"name":"Department of Cardiology Medical University of South Carolina Mt Pleasant South Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dursun","family":"Aras","sequence":"additional","affiliation":[{"name":"Department of Cardiology Ankara City Hospital Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4611-3687","authenticated-orcid":false,"given":"Rakesh","family":"Gopinathannair","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kansas City Heart Rhythm Institute and Research Foundation Kansas City Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,7,7]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.13511"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.2007.04990.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eur163"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2019.07.018"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.116.004638"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-018-0421-4"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.119.007811"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.02.116"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.03.069"}],"container-title":["Journal of Cardiovascular 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