{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T15:40:05Z","timestamp":1791214805041,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2021,8,26]],"date-time":"2021-08-26T00:00:00Z","timestamp":1629936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Conduction system pacing (CSP) has emerged as an ideal physiologic pacing strategy for patients with permanent pacing indications. We sought to evaluate the safety and feasibility of CSP in a consecutive series of unselected patients with congenital heart disease (CHD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Consecutive patients with CHD in which CSP was attempted were included. Safety and feasibility, implant tools and electrical parameters at implant and at follow\u2010up were evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 20 patients were included (10 with a previous device). A total of 10 patients had complex forms of CHD, 9 moderate defects and 1 a simple defect. CSP was achieved in 75% of cases (10 His bundle pacing, 5 left bundle branch pacing) with left ventricular septal pacing in the remaining 5 patients. Procedure times and fluoroscopy times were prolongued (126\u2009\u00b1\u200982\u2009min and 27\u2009\u00b1\u200930\u2009min, respectively). Ventricular lead implant times widely varied ranging from 4 to 115\u2009min, (mean 31\u2009\u00b1\u200928\u2009min) and the use of multiple delivery sheaths was frequent (50%). The QRS width was reduced from 145\u2009\u00b1\u200936\u2009ms at baseline to 116\u2009\u00b1\u200918\u2009ms with CSP. Implant electrical parameters included: CSP pacing threshold 0.95\u2009\u00b1\u20090.65\u2009V; R wave amplitude 9.2\u2009\u00b1\u20098.8\u2009mV and pacing impedance 632\u2009\u00b1\u2009183\u2009Ohms, and remained stable at a median follow\u2010up of 478 days (interquartile range: 225\u2013567). Systemic ventricle systolic function and NYHA class (1.50\u2009\u00b1\u20090.51 vs. 1.10\u2009\u00b1\u20090.31;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.008) significantly improved at follow\u2010up. Lead revision was required in one patient at Day 4.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Permanent CSP is safe and feasible in patients with CHD although implant technique is complex.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.15213","type":"journal-article","created":{"date-parts":[[2021,8,18]],"date-time":"2021-08-18T02:39:31Z","timestamp":1629254371000},"page":"2692-2703","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Safety and feasibility of conduction system pacing in patients with congenital heart disease"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6783-0138","authenticated-orcid":false,"given":"\u00d3scar","family":"Cano","sequence":"first","affiliation":[{"name":"Electrophysiology Section, Adult Congenital Heart Disease Section and Paediatric Cardiology Section, Cardiology Department Hospital Universitari i Polit\u00e8cnic La Fe Valencia Spain"},{"name":"Centro de Investigaciones Biom\u00e9dicas en RED en Enfermedades Cardiovasculares (CIBERCV) Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gopi","family":"Dandamudi","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Cardiovascular Service Line, Cardiology CHI\u2010Franciscan Health System Tacoma Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert D.","family":"Schaller","sequence":"additional","affiliation":[{"name":"Electrophysiology Section, Division of Cardiovascular Medicine University of Pennsylvania Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00edctor","family":"P\u00e9rez\u2010Rosell\u00f3","sequence":"additional","affiliation":[{"name":"Electrophysiology Section, Adult Congenital Heart Disease Section and Paediatric Cardiology Section, Cardiology Department Hospital Universitari i Polit\u00e8cnic La Fe Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hebert D.","family":"Ayala","sequence":"additional","affiliation":[{"name":"Electrophysiology Section, Adult Congenital Heart Disease Section and Paediatric Cardiology Section, Cardiology Department Hospital Universitari i Polit\u00e8cnic La Fe Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maite","family":"Izquierdo","sequence":"additional","affiliation":[{"name":"Electrophysiology Section, Adult Congenital Heart Disease Section and Paediatric Cardiology Section, Cardiology Department Hospital Universitari i Polit\u00e8cnic La Fe Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaqu\u00edn","family":"Osca","sequence":"additional","affiliation":[{"name":"Electrophysiology Section, Adult Congenital Heart 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