{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T18:11:55Z","timestamp":1778782315442,"version":"3.51.4"},"reference-count":9,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,9,3]],"date-time":"2021-09-03T00:00:00Z","timestamp":1630627200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      During nonselective His bundle (HB) pacing, it is clinically important to confirm His bundle capture versus right ventricular septal (RVS) capture. The present study aimed to validate the hypothesis that during HB capture, left ventricular lateral wall activation time, approximated by the V\n                      <jats:sub>6<\/jats:sub>\n                      R\u2010wave peak time (V\n                      <jats:sub>6<\/jats:sub>\n                      RWPT), will not be longer than the corresponding activation time during native conduction.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Consecutive patients with permanent HB pacing were recruited; cases with abnormal His\u2010ventricle interval or left bundle branch block were excluded. Two corresponding intervals were compared: stimulus\u2010V\n                      <jats:sub>6<\/jats:sub>\n                      RWPT and native HB potential\u2010V\n                      <jats:sub>6<\/jats:sub>\n                      RWPT. The difference between these two intervals (delta V\n                      <jats:sub>6<\/jats:sub>\n                      RWPT), which was diagnostic of lack of HB capture, was identified using receiver operating characteristic (ROC) curve analysis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 723 electrocardiograms (ECGs) (219 with native rhythm, 172 with selective HB, 215 with nonselective HB, and 117 with RVS capture) were obtained from 219 patients. The native HB\u2010V\n                      <jats:sub>6<\/jats:sub>\n                      RWPT, nonselective\u2010, and selective\u2010HB paced V\n                      <jats:sub>6<\/jats:sub>\n                      RWPT were nearly equal, while RVS V\n                      <jats:sub>6<\/jats:sub>\n                      RWPT was 32.0 (\u00b19.5)\u2009ms longer. The ROC curve analysis indicated delta V\n                      <jats:sub>6<\/jats:sub>\n                      RWPT\u2009&gt;\u200912 ms as diagnostic of lack of HB capture (specificity of 99.1% and sensitivity of 100%). A blinded observer correctly diagnosed 96.7% (321\/332) of ECGs using this criterion.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      We validated a novel criterion for HB capture that is based on the physiological left ventricular activation time as an individualized reference. HB capture can be diagnosed when paced V\n                      <jats:sub>6<\/jats:sub>\n                      RWPT does not exceed the value obtained during native conduction by more than 12\u2009ms, while longer paced V\n                      <jats:sub>6<\/jats:sub>\n                      RWPT indicates RVS capture.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.15233","type":"journal-article","created":{"date-parts":[[2021,8,29]],"date-time":"2021-08-29T01:16:37Z","timestamp":1630199797000},"page":"3010-3018","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Novel approach to diagnosis of His bundle capture using individualized left ventricular lateral wall activation time as reference"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3318-6601","authenticated-orcid":false,"given":"Marek","family":"Jastrz\u0119bski","sequence":"first","affiliation":[{"name":"First Department of Cardiology, Interventional Electrocardiology and Hypertension Jagiellonian University Medical College  Krak\u00f3w Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5644-5963","authenticated-orcid":false,"given":"Pawe\u0142","family":"Moskal","sequence":"additional","affiliation":[{"name":"First Department of Cardiology, Interventional Electrocardiology and Hypertension Jagiellonian University Medical College  Krak\u00f3w Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piotr","family":"Kukla","sequence":"additional","affiliation":[{"name":"Department of Cardiology H. Klimontowicz Specialistic Hospital  Gorlice Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agnieszka","family":"Bednarek","sequence":"additional","affiliation":[{"name":"First Department of Cardiology, Interventional Electrocardiology and Hypertension Jagiellonian University Medical College  Krak\u00f3w Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grzegorz","family":"Kie\u0142basa","sequence":"additional","affiliation":[{"name":"First Department of Cardiology, Interventional Electrocardiology and Hypertension Jagiellonian University Medical College  Krak\u00f3w Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marek","family":"Rajzer","sequence":"additional","affiliation":[{"name":"First Department of Cardiology, Interventional Electrocardiology and Hypertension Jagiellonian University Medical College  Krak\u00f3w Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karol","family":"Curila","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Third Faculty of Medicine Charles University and University Hospital Kralovske Vinohrady  Prague Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2230-100X","authenticated-orcid":false,"given":"Pugazhendhi","family":"Vijayaraman","sequence":"additional","affiliation":[{"name":"Geisinger Heart Institute Geisinger Commonwealth School of Medicine  Wilkes\u2010Barre Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,9,3]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2017.10.039"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euz275"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2021.02.021"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/anec.12323"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.191095"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.14834"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euaa244"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.118.007052"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2019.04.032"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.15233","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jce.15233","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.15233","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T05:30:21Z","timestamp":1693200621000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.15233"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,3]]},"references-count":9,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["10.1111\/jce.15233"],"URL":"https:\/\/doi.org\/10.1111\/jce.15233","archive":["Portico"],"relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2021.05.28.21257962","asserted-by":"object"}]},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,3]]},"assertion":[{"value":"2021-06-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}