{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,29]],"date-time":"2025-05-29T09:09:47Z","timestamp":1748509787880,"version":"3.37.3"},"reference-count":35,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,9,8]],"date-time":"2021-09-08T00:00:00Z","timestamp":1631059200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The distance from the descending aorta (DA) to the posterior wall of the left atrium (LA) is variable. We aimed to determine whether the proximity between the DA and the left inferior pulmonary vein (LIPV) ostium has an impact on biophysical parameters and cryoballoon (CB) ablation efficacy during LIPV freezing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients referred for CB\u2010ablation of atrial fibrillation (AF) in two high\u2010volume centers were included. Cryoablation data were collected prospectively for each patient. The anatomical relationships between the LIPV and the DA (distance LIPV ostium\u2010DA, presence of an aortic imprint on the posterior aspect of the LIPV) were then retrospectively analysed on the LA computed tomography scans realized before AF ablation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 350 patients were included (70% men, 59.7\u2009\u00b1\u200911.5 years). The decrease in the Ostium\u2010DA distance was significantly correlated to the increase in the time\u2010to\u2010isolation (TTI) (<jats:italic>r<\/jats:italic>\u2009=\u2009\u2212.31; <jats:italic>p<\/jats:italic>\u2009=\u2009.036), with less negative temperature (<jats:italic>r<\/jats:italic>\u2009=\u2009\u2212.11; <jats:italic>p<\/jats:italic>\u2009=\u2009.045). Similarly, the presence of an aortic imprint on the LIPV was associated with a longer TTI (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). The analysis of redo procedures data shows a trend toward the presence of shorter ostium\u2010DA distances (15.3\u2009\u00b1\u20093.29 vs. 18.1\u2009\u00b1\u20094.99, <jats:italic>p<\/jats:italic>\u2009=\u2009.15) and more frequent aortic imprints (63.6% vs. 47.5%, <jats:italic>p<\/jats:italic>\u2009=\u2009.34) in patients with LIPV reconnection as opposed to patients without reconnection in the LIPV.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our findings indicated that the DA seems to have a \u201cradiator\u201d effect influencing LIPV cryoablation parameters during CB\u2010ablation. Additional studies will be needed to elucidate whether this biophysical influence has a clinical impact in LIPVs reconnections.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.15234","type":"journal-article","created":{"date-parts":[[2021,8,29]],"date-time":"2021-08-29T05:14:10Z","timestamp":1630214050000},"page":"2943-2952","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Distance between the descending aorta and the left inferior pulmonary vein as a determinant of biophysical parameters during paroxysmal atrial fibrillation cryoablation"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7108-3427","authenticated-orcid":false,"given":"Karim","family":"Benali","sequence":"first","affiliation":[{"name":"Department of Cardiology Saint\u2010Etienne University Hospital  Saint\u2010Priest\u2010En\u2010Jarez France"},{"name":"University of Nancy, CHU Nancy, INSERM\u2010IADI, U947  Vand\u0153uvre l\u00e8s\u2010Nancy France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3302-9988","authenticated-orcid":false,"given":"Antoine","family":"Da Costa","sequence":"additional","affiliation":[{"name":"Department of Cardiology Saint\u2010Etienne University Hospital  Saint\u2010Priest\u2010En\u2010Jarez France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3328-5239","authenticated-orcid":false,"given":"Laurent","family":"Macle","sequence":"additional","affiliation":[{"name":"Department of Medicine Electrophysiology Service at the Montreal Heart Institute  Montreal Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nefissa","family":"Hammache","sequence":"additional","affiliation":[{"name":"University of Nancy, CHU Nancy, INSERM\u2010IADI, U947  Vand\u0153uvre l\u00e8s\u2010Nancy France"},{"name":"Department of Cardiology Nancy University Hospital  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