{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T14:39:30Z","timestamp":1792075170508,"version":"4.4.0"},"reference-count":30,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,5,22]],"date-time":"2022-05-22T00:00:00Z","timestamp":1653177600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Implantation depth and membranous septum (MS) length have been established as the predictors of new\u2010onset conduction disturbance (CD) after transcatheter aortic valve replacement (TAVR) for tricuspid aortic valve (TAV) stenosis. However, little is known about the predictors with bicuspid aortic valve (BAV). This study investigated the role of MS length and implantation depth in predicting CD following TAVR with a balloon\u2010expandable valve in patients with BAV.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study analyzed 169 patients who underwent TAVR for BAV with balloon\u2010expandable valve, and TAV cohort was established as a control group using propensity score (PS) matching. The primary endpoints were in\u2010hospital new permanent pacemaker implantation (PPI) and new\u2010onset CD (the composite outcome of new\u2010onset left bundle branch block and new PPI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      PPI developed in 14 patients (8.3%) and new\u2010onset CD in 37 patients (21.9%) in the\u00a0BAV cohort. Multivariate analysis revealed severe left ventricle outflow tract\u00a0(LVOT) calcification (odds ratio [OR]: 5.83, 95% confidence interval [CI]: 1.08\u201331.5,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.0407) and implantation depth\u2014MS length (OR: 1.30, 95% CI: 1.12\u20131.51,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.0005) as the predictors of new\u2010onset CD within the BAV cohort. The matched comparison between BAV and TAV groups showed similar MS length (3.0 vs. 3.2\u2009mm,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.5307), but valves were implanted more deeply in the BAV group than in the TAV group (3.9 vs. 3.0\u2009mm,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.0001). New\u2010onset CD was more frequent in patients who had BAV (22.3% vs. 13.9%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.0458).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The implantation depth\u2014MS length, and severe LVOT calcification predicted new\u2010onset CD following TAVR in BAV with balloon\u2010expandable valve. Among BAV patients, valves were implanted more deeply compared to TAV patients. High deployment technique could be considered to avoid new\u2010onset CD in BAV anatomy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.15525","type":"journal-article","created":{"date-parts":[[2022,5,11]],"date-time":"2022-05-11T10:16:05Z","timestamp":1652264165000},"page":"1576-1586","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Predictors of conduction disturbances after transcatheter aortic valve implantation with balloon\u2010expandable valve for bicuspid aortic valve stenosis"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1562-9437","authenticated-orcid":false,"given":"Hirokazu","family":"Miyashita","sequence":"first","affiliation":[{"name":"Department of Cardiology, Heart and Lung Center Helsinki University and Helsinki University Central Hospital  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8570-5901","authenticated-orcid":false,"given":"Noriaki","family":"Moriyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Futoshi","family":"Yamanaka","sequence":"additional","affiliation":[{"name":"Department of Cardiology Shonan Kamakura General Hospital  Kamakura Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeru","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Cardiology Shonan Kamakura General Hospital  Kamakura Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi","family":"Lehtola","sequence":"additional","affiliation":[{"name":"Department of Cardiology Oulu University Hospital  Oulu Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jarkko","family":"Piuhola","sequence":"additional","affiliation":[{"name":"Department of Cardiology Oulu University Hospital  Oulu Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matti","family":"Niemel\u00e4","sequence":"additional","affiliation":[{"name":"Department of Cardiology Oulu University Hospital  Oulu Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mika","family":"Laine","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Heart and Lung Center Helsinki University and Helsinki University Central Hospital  Helsinki 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