{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T22:58:18Z","timestamp":1762642698706,"version":"3.37.3"},"reference-count":15,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T00:00:00Z","timestamp":1653523200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Left bundle branch area pacing (LBBAP) is a form of conduction system pacing. Long\u2010term data on the safety and performance of LBBAP 1 year postdevice implantation has not been well described.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>Sixty\u2010five patients (49% females) who received LBBAP for bradycardia indications using the SelectSecure 3830 lead (Medtronic) were retrospectively evaluated. Clinical variables were examined. Lead parameters were obtained at implant and during regular follow\u2010up. Mean age of patients was 75.7\u2009\u00b1\u200910.1 years with left ventricular ejection fraction 59.8\u2009\u00b1\u200910.4%. Indications for pacing were atrioventricular block 55%, sinus node dysfunction 19%, tachy\u2010brady syndrome 15%, atrioventricular node ablation 8%, and bail out cardiac resynchronization therapy 3%. Mean baseline QRS measured 120\u2009\u00b1\u200938\u2009ms, paced QRS duration was 138\u2009\u00b1\u200922ms. Paced QRS narrowed by 24\u2009ms in those with pre\u2010existing left bundle branch block (BBB), increased by 1\u2009ms in those with pre\u2010existing right BBB, and increased by 42\u2009ms in those with no BBB. LBBAP threshold at implant was 0.521\u2009\u00b1\u20090.153\u2009V at 0.4\u2009ms, and increased to 0.654\u2009\u00b1\u20090.186\u2009V at 3 months (+26%), 0.707\u2009\u00b1\u20090.186\u2009V at 6 months (+36%), and 0.772\u2009\u00b1\u20090.220\u2009V at 12 months (+48%). Patients with left BBB showed the maximum benefit with QRS narrowing 24\u2009ms. Pacing impedance remained unchanged with no procedure\u2010related complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>LBBAP is a durable form of conduction system pacing with pacing thresholds remaining relatively stable over 12 months post device implantation. Patients with left BBB display the narrowest paced QRS.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.15545","type":"journal-article","created":{"date-parts":[[2022,5,19]],"date-time":"2022-05-19T06:51:20Z","timestamp":1652943080000},"page":"1529-1536","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Durability of left bundle branch area pacing"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5971-2158","authenticated-orcid":false,"given":"Nikhil A.","family":"Mehta","sequence":"first","affiliation":[{"name":"Department of Electrophysiology Lehigh Valley Heart Institute Allentown Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bilal","family":"Saqi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Syed R. A.","family":"Sabzwari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2511-2119","authenticated-orcid":false,"given":"Rahul","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Cardiology Lehigh Valley Heart Institute Allentown Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Apurva","family":"Vyas","sequence":"additional","affiliation":[{"name":"Department of Cardiology Lehigh Valley Heart Institute Allentown Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3597-8282","authenticated-orcid":false,"given":"Jeffrey","family":"Gordon","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology Lehigh Valley Heart Institute Allentown Pennsylvania 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outcomes of left bundle branch area pacing compared to right ventricular pacing: results from the GEISINGER\u2010RUSH conduction system pacing registry","volume":"18","author":"Sharma P","year":"2021","journal-title":"Heart Rhythm"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2021.07.057"}],"container-title":["Journal of Cardiovascular 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