{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T22:53:18Z","timestamp":1790635998657,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,9,18]],"date-time":"2022-09-18T00:00:00Z","timestamp":1663459200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Multiple groups have reported on the usefulness of ablating in atrial regions exhibiting abnormal electrograms during atrial fibrillation (AF). Still, previous studies have suggested that ablation outcomes are highly operator\u2010 and center\u2010dependent. This study sought to evaluate a novel machine learning software algorithm named\u00a0VX1 (Volta Medical), trained to adjudicate multipolar electrogram dispersion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study was a prospective, multicentric, nonrandomized study conducted to assess the feasibility of generating VX1 dispersion maps. In 85 patients, 8 centers, and 17 operators, we compared the acute and long\u2010term outcomes after ablation in regions exhibiting dispersion between primary and satellite centers. We also compared outcomes to a control group in which dispersion\u2010guided ablation was performed visually by trained operators.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The study population included 29% of long\u2010standing persistent AF. AF termination occurred in 92% and 83% of the patients in primary and satellite centers, respectively,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.31. The average rate of freedom from documented AF, with or without antiarrhythmic drugs (AADs), was 86% after a single procedure, and 89% after an average of 1.3 procedures per patient (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.4). The rate of freedom from any documented atrial arrhythmia, with or without AADs, was 54% and 73% after a single or an average of 1.3 procedures per patient, respectively (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). No statistically significant differences between outcomes of the primary versus satellite centers were observed for one (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.8) or multiple procedures (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.4), or between outcomes of the entire study population versus the control group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.2). Interestingly, intraprocedural AF termination and type of recurrent arrhythmia (i.e., AF vs. AT) appear to be predictors of the subsequent clinical course.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>VX1, an expertise\u2010based artificial intelligence software solution, allowed for robust center\u2010to\u2010center standardization of acute and long\u2010term ablation outcomes after electrogram\u2010based ablation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.15657","type":"journal-article","created":{"date-parts":[[2022,8,22]],"date-time":"2022-08-22T02:24:40Z","timestamp":1661135080000},"page":"2250-2260","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["Artificial intelligence software standardizes electrogram\u2010based ablation outcome for persistent atrial fibrillation"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8499-7167","authenticated-orcid":false,"given":"Julien","family":"Seitz","sequence":"first","affiliation":[{"name":"St. Joseph Hospital Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Th\u00e9ophile Mohr","family":"Durdez","sequence":"additional","affiliation":[{"name":"Volta Medical Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean P.","family":"Albenque","sequence":"additional","affiliation":[{"name":"Clinique Pasteur Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Pisapia","sequence":"additional","affiliation":[{"name":"St. Joseph Hospital Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edouard","family":"Gitenay","sequence":"additional","affiliation":[{"name":"St. Joseph Hospital Marseille 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