{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T19:39:43Z","timestamp":1793129983102,"version":"4.5.0"},"reference-count":25,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T00:00:00Z","timestamp":1664496000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The novel method of left bundle branch pacing (LBBP) has been reported to achieve better electrical and mechanical synchrony in the left ventricle than conventional right ventricular pacing (RVP). However, its effects on right ventricle (RV) performance are still unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive patients undergoing dual\u2010chamber pacemaker (PM) implantation for sick sinus syndrome (SSS) with normal cardiac function and a narrow QRS complex were recruited for the study. The pacing characteristics and echocardiogram parameters were measured to evaluate RV function, interventricular and RV synchrony, and were compared between ventricular pacing\u2010on and native\u2010conduction modes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 84 patients diagnosed with SSS and an indication for pacing therapy were enrolled. Forty\u2010two patients (50%; mean age 65.50\u2009\u00b1\u20099.30 years; 35% male) underwent successful LBBP and 42 patients (50%; mean age 69.26\u2009\u00b1\u200910.08 years; 33% male) RVSP, respectively. Baseline characteristics were similar between the two groups. We found no significant differences in RV function [RV\u2010FAC (Fractional Area Change)%, 47.13\u2009\u00b1\u20095.69 versus 48.60\u2009\u00b1\u20095.83, <jats:italic>p<\/jats:italic>\u2009=\u2009.069; Endo\u2010GLS (Global Longitudinal Strain)%, \u221228.88\u2009\u00b1\u20094.94 versus \u221229.82\u2009\u00b1\u20095.35, <jats:italic>p<\/jats:italic>\u2009=\u2009.114; Myo\u2010GLS%, \u221225.72\u2009\u00b1\u20094.75 versus \u221225.72\u2009\u00b1\u20095.21, <jats:italic>p<\/jats:italic>\u2009=\u2009.559; Free Wall St%, 27.40\u2009\u00b1\u20098.03 versus \u221228.71\u2009\u00b1\u20097.34, <jats:italic>p<\/jats:italic>\u2009=\u2009.304] between the native\u2010conduction and LBBP capture modes, while the RVSP capture mode was associated with a significant reduction in the above parameters compared with the native\u2010conduction mode (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.0001). The interventricular synchrony in the LBBP group was also superior to the RVSP group significantly.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>LBBP is a pacing technique that seems to associate with a positive and protective impact on RV performance.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.15675","type":"journal-article","created":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T06:30:34Z","timestamp":1663655434000},"page":"2614-2624","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Impact on right ventricular performance in patients undergoing permanent pacemaker implantation: Left bundle branch pacing versus right ventricular septum pacing"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7655-6652","authenticated-orcid":false,"given":"Xinyi","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Ultrasound Medicine Xiamen Cardiovascular Hospital of Xiamen University, School of Medicine, Xiamen University  Xiamen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5406-9711","authenticated-orcid":false,"given":"Manxin","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Cardiology Xiamen Cardiovascular Hospital of Xiamen University, School of Medicine, Xiamen University  Xiamen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shufen","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Cardiology Xiamen Cardiovascular Hospital of Xiamen University, School of Medicine, Xiamen University  Xiamen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7120-2203","authenticated-orcid":false,"given":"Jincun","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Cardiology Xiamen Cardiovascular Hospital of Xiamen University, School of Medicine, Xiamen University  Xiamen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linlin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Cardiology Xiamen Cardiovascular Hospital of Xiamen University, School of Medicine, Xiamen University  Xiamen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Cardiac Function Xiamen Cardiovascular Hospital of Xiamen University, School of Medicine, Xiamen University  Xiamen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunhui","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Medicine Xiamen Cardiovascular Hospital of Xiamen University, School of Medicine, Xiamen University  Xiamen 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