{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T04:34:27Z","timestamp":1769747667396,"version":"3.49.0"},"reference-count":37,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,11,24]],"date-time":"2022-11-24T00:00:00Z","timestamp":1669248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Data on utilization, major complications, and in\u2010hospital mortality of catheter ablation (CA) for sarcoidosis\u2010related ventricular tachycardia (VT) are limited. We sought to determine the outcomes of sarcoidosis\u2010related VT, and incidence and predictors of complications associated with the CA procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We queried the 2002\u20132018 National Inpatient Sample database to identify patients aged \u226518 years with sarcoidosis admitted with VT. A 1:3 propensity score\u2010matched (PSM) analysis was used to compare patient outcomes between CA and medically managed groups. Multivariable regression was performed to determine independent predictors of in\u2010hospital mortality and procedural complications associated with the CA procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 3220 sarcoidosis patients with VT, 132 (4.1%) underwent CA. Patients who underwent CA were younger, male predominant, more likely Caucasian, had differences in baseline comorbidities including more likely to have heart failure, less likely to have prior myocardial infarction, COPD, or severe renal disease, had a higher mean household income, and more likely admitted to a larger\/urban teaching hospital. After PSM, we examined 106 CA cases and 318 medically managed cases. There was a trend toward a lower in\u2010hospital mortality rate in the CA group when compared to the medically managed group (1.9% vs. 6.6%, <jats:italic>p<\/jats:italic>\u2009=\u20090.08). The most common complications were pericardial drainage (5.3%), postoperative hemorrhage (3.8%), accidental puncture periprocedure (3.0%), and cardiac tamponade (2.3%). Independent predictors of in\u2010hospital mortality and procedural complications among the CA group included congestive heart failure (odds ratio\u00a0[OR], 13.2; 95% confidence interval\u00a0[CI], 1.7\u2013104.2) and mild to moderate renal disease (OR, 3.9; 95% CI, 1.1\u201313.3).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Compared to patients with sarcoidosis\u2010related VT who received medical therapy alone, those who underwent CA have a trend for a lower mortality rate despite procedure\u2010related complications occurring as high as 9.1%. Additional studies are recommended to better evaluate the benefits and risks of VT ablation in this group.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.15708","type":"journal-article","created":{"date-parts":[[2022,11,6]],"date-time":"2022-11-06T20:18:10Z","timestamp":1667765890000},"page":"2585-2598","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Outcomes of catheter ablation for ventricular tachycardia in patients with sarcoidosis: Insights from the\u00a0National Inpatient Sample database (2002\u20132018)"],"prefix":"10.1111","volume":"33","author":[{"given":"Jian Liang","family":"Tan","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Disease, Cooper University Health Care Cooper Medical School of Rowan University  Camden New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chengyue","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Medicine Westchester Medical Center  Valhalla New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin Z.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Cardiology Mayo Clinic Arizona  Phoenix Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Gaughan","sequence":"additional","affiliation":[{"name":"Cooper Research Institute Cooper Medical School of Rowan University  Camden New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8283-3211","authenticated-orcid":false,"given":"Sei","family":"Iwai","sequence":"additional","affiliation":[{"name":"Department of Cardiology Westchester Medical Center  Valhalla New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3129-6161","authenticated-orcid":false,"given":"Andrea M.","family":"Russo","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Disease, Cooper University Health Care Cooper Medical School of Rowan University  Camden New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,11,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra071714"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2014.03.043"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.11.041"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.116.005001"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.4960270409"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2008.10.039"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2006.03.031"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.10.054"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2019.05.007"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2019.09.015"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2021.4738"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eux077"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2018.05.007"},{"key":"e_1_2_9_15_1","volume-title":"Healthcare Cost and Utilization Project (HCUP)","author":"HCUP National Inpatient Sample (NIS)","year":"2018"},{"key":"e_1_2_9_16_1","volume-title":"National Inpatient Sample (NIS) Comparison Report. 2015. 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