{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T18:01:19Z","timestamp":1781632879786,"version":"3.54.5"},"reference-count":27,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,11,9]],"date-time":"2022-11-09T00:00:00Z","timestamp":1667952000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Catheter\u2010ablation (CA) of consecutive left atrial tachycardias (LAT) can be challenging. Pulsed field ablation (PFA) yields a novel nonthermal CA technology for treatment of atrial fibrillation (AF). There is no data regarding PFA of LAT. This study sought to investigate PFA of consecutive LAT following prior CA of AF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive patients with LAT underwent ultrahigh\u2010density (UHDx) mapping. Subsequent to identification of the AT mechanism, PFA was performed at the assumed critical sites for LAT maintenance. Continuous ablation lines were performed if required and evaluated with pre\u2010 and post\u2010PFA HDx\u2010mapping.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifteen patients (age 70\u2009\u00b1\u200910, male 73%) who underwent 3.6\u2009\u00b1\u20092 prior AF\u2010CA procedures were included. The total mean procedure and fluoroscopy times were 141\u2009\u00b1\u200943 and 18\u2009\u00b1\u200910\u2009min, respectively. All 19 of 19 (100%) LAT were successfully ablated with PFA. Two AT located at the right atria required RF\u2010ablation. LAT were identified as localized reentry (<jats:italic>n<\/jats:italic>\u2009=\u20091) and macro\u2010reentry LAT (<jats:italic>n<\/jats:italic>\u2009=\u200918) and targeted with PFA. All LAT terminated with PFA either to sinus rhythm (9\/15) or a secondary AT (6\/15 and subsequently to SR); 63% (12\/19) terminated with the first PFA\u2010application. All lines (13 roof, 11 anterior, 1 mitral) were blocked. LA\u2010posterior\u2010wall isolation (LAPWI) was successfully achieved when performed (10\/10). AF\/AT free survival was 80% (12\/15) after 153 [88\u2013207] days of follow\u2010up. No procedure\u2010related complications occurred.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>PFA of consecutive LAT is feasible and safe. Successful creation of ablation lines and LAPWI can be achieved in a short time. PFA may offer the opportunity for effective ablation of atrial arrhythmias beyond AF.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.15713","type":"journal-article","created":{"date-parts":[[2022,10,19]],"date-time":"2022-10-19T12:55:22Z","timestamp":1666184122000},"page":"2431-2443","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Pulsed field ablation in patients with complex consecutive atrial tachycardia in conjunction with ultra\u2010high density mapping: Proof of concept"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7561-7185","authenticated-orcid":false,"given":"Melanie A.","family":"Gunawardene","sequence":"first","affiliation":[{"name":"Asklepios Hospital St. Georg Department of Cardiology and Intensive Care Medicine Hamburg Germany"},{"name":"Semmelweis University Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin 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and Intensive Care Medicine Hamburg Germany"},{"name":"Semmelweis University Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja","family":"Hedenus","sequence":"additional","affiliation":[{"name":"Asklepios Hospital St. Georg Department of Cardiology and Intensive Care Medicine Hamburg Germany"},{"name":"Semmelweis University Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahin","family":"Wahedi","sequence":"additional","affiliation":[{"name":"Asklepios Hospital St. Georg Department of Cardiology and Intensive Care Medicine Hamburg Germany"},{"name":"Semmelweis University Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9738-4685","authenticated-orcid":false,"given":"Omar","family":"Anwar","sequence":"additional","affiliation":[{"name":"Asklepios Hospital St. Georg Department of Cardiology and Intensive Care Medicine Hamburg 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