{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T22:57:17Z","timestamp":1784329037902,"version":"3.55.0"},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T00:00:00Z","timestamp":1668470400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Monomorphic ventricular tachycardia (VT) is rare in patients with hypertrophic cardiomyopathy (HCM), management of which is challenging. Limited data exists on the utility of catheter ablation for the treatment of VT in this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We aimed to assess clinical outcomes of catheter ablation for VT in HCM patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A systematic search, without language restriction, using PubMed, EMBASE, SCOPUS, Google Scholar, and ClinicalTrials.gov was performed. The meta\u2010analysis was performed using a <jats:italic>meta\u2010package<\/jats:italic> for R version 4.0\/RStudio version 1.2 and Freeman Tukey double arcsine method to establish the variance of raw proportions. Outcomes measured included (1) acute procedure success (defined as noninducible for clinical VT),\u00a0(2) freedom from VT at follow\u2010up, (3) mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This systematic review of six studies (three from the\u00a0United States and three from Japan) incorporated a total of 68 drug\u2010refractory HCM patients who underwent VT radiofrequency catheter ablation (mean age 57.6\u2009\u00b1\u200913.3\u2009years, mean LVEF 45.8\u2009\u00b1\u200915.4%, 85% men, maximum septal wall thickness 17.4\u2009\u00b1\u20094.6\u2009mm, and 32.3% with an apical aneurysm). Acute procedural success was achieved in 84.5% patients (95% confidence interval\u00a0[CI]: 70.6%\u201395.2%) with 27.9% patients had recurrent VT requiring multiple ablations (median 1, IQR 1\u20133). During the follow\u2010up period (18.3\u2009\u00b1\u200911.7\u2009months), the pooled incidence of freedom from recurrent VT after index procedure was 70.2% (95% CI: 51.9%\u201386.2%), while after the last ablation was 82.8% (95% CI: 57%\u201399.2%). There were two deaths during follow\u2010up, one from heart failure and one from SCD 0.8% (95% CI: 0%\u20135.8%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The results of our pooled analysis demonstrated that catheter ablation for VT in HCM patients was associated with high acute procedural success, and reduced VT recurrence\u2014findings comparable to previously published reports in other disease substrates.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.15739","type":"journal-article","created":{"date-parts":[[2022,11,6]],"date-time":"2022-11-06T20:20:52Z","timestamp":1667766052000},"page":"219-224","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Clinical outcomes of radiofrequency catheter ablation of ventricular tachycardia in patients with hypertrophic cardiomyopathy"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6857-7418","authenticated-orcid":false,"given":"Jalaj","family":"Garg","sequence":"first","affiliation":[{"name":"Division of Cardiology, Cardiac Arrhythmia Service Loma Linda University Health Loma Linda California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakrin","family":"Kewcharoen","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cardiac Arrhythmia Service Loma Linda University Health Loma Linda California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1345-0719","authenticated-orcid":false,"given":"Kuldeep","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Beaumont Hospital Oakland University William Beaumont School of Medicine Royal Oak Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohit","family":"Turagam","sequence":"additional","affiliation":[{"name":"Helmsley Electrophysiology Center Icahn School of Medicine at Mount Sinai New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7734-8660","authenticated-orcid":false,"given":"Rahul","family":"Bhardwaj","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cardiac Arrhythmia Service Loma Linda University Health Loma Linda California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tahmeed","family":"Contractor","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cardiac Arrhythmia Service Loma Linda University Health Loma Linda California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravi","family":"Mandapati","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cardiac Arrhythmia Service Loma Linda University Health Loma Linda California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1492-2693","authenticated-orcid":false,"given":"Dhanunjaya","family":"Lakkireddy","sequence":"additional","affiliation":[{"name":"Kansas City Heart Rhythm Institute and Research Foundation Kansas City Kansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,15]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.110.957290"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2010.01875.x"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2010.05.022"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2017.12.020"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.14508"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eur344"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.11.063"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2007.02.001"},{"key":"e_1_2_3_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.15231"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.15739","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jce.15739","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.15739","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T12:17:33Z","timestamp":1692447453000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.15739"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,15]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["10.1111\/jce.15739"],"URL":"https:\/\/doi.org\/10.1111\/jce.15739","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,15]]},"assertion":[{"value":"2022-06-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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