{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T16:37:39Z","timestamp":1776098259208,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,1,22]],"date-time":"2023-01-22T00:00:00Z","timestamp":1674345600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Substrate\u2010based ablation for ventricular tachycardia (VT) using Ripple map (RM) is an effective treatment strategy for patients with ischemic cardiomyopathy but has yet to be evaluated in patients with nonischemic cardiomyopathy (NICMO). The aim of this study is to determine the feasibility and effectiveness of an RM\u2010based\u00a0ablation for NICMO patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>This was a single\u2010center, retrospective study including all NICMO patients undergoing VT ablation at St Vincent Hospital between January 1, 2018 and January 12, 2019. Retrospective RM analysis was performed on those that had a substrate\u2010based ablation to identify the location and number of Ripple channels as well as their proximity to ablation lesions. Thirty\u2010three patients met the inclusion criteria and had a median age of 65 (58, 73.5) with 15.2% of the population being female, and were followed for a median duration of 451 (217.5, 586.5) days. Of these patients, 23 (69.7%) had a substrate\u2010based ablation with a median procedural duration of 196.4 (186.8, 339)\u2009min, 1946 (517, 2750) points collected per map, and 277 (141, 554) points were within the scar. Two (8.6%) procedural complications occurred, and 7 (30.4%) patients had VT recurrence during follow\u2010up. RM analysis revealed an average of two Ripple channels and the patients without VT recurrence had ablation performed closer to the Ripple channels: 0 (0, 4.7) versus 14.3 (0, 23.5)\u2009cm; <jats:italic>p<\/jats:italic>\u2009=\u2009.02.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>An RM\u2010based\u00a0substrate ablation can be performed in NICMO patients and ablation within Ripple channels is a predictor of VT freedom.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.15814","type":"journal-article","created":{"date-parts":[[2023,1,14]],"date-time":"2023-01-14T20:09:59Z","timestamp":1673726999000},"page":"652-661","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Ripple mapping in ventricular tachycardia substrate mapping and ablation of nonischemic ventricular tachycardia"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9370-4370","authenticated-orcid":false,"given":"Jasen L.","family":"Gilge","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Division of Cardiology Ascension St Vincent Medical Group  Indianapolis Indiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandeep A.","family":"Joshi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Cardiology Ascension St Vincent Medical Group  Indianapolis Indiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Girish V.","family":"Nair","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Cardiology Ascension St Vincent Medical Group  Indianapolis Indiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bradley 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