{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T08:59:52Z","timestamp":1793437192954,"version":"4.5.0"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T00:00:00Z","timestamp":1685059200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Ventricular arrhythmias (VAs) are the most common cause of death in patients with repaired Tetralogy of Fallot (rTOF). However, risk stratifying remains challenging. We examined outcomes following programmed ventricular stimulation (PVS) with or without subsequent ablation in patients with rTOF planned for pulmonary valve replacement (PVR).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We included all consecutive patients with rTOF referred to our institution from 2010 to 2018 aged\u2009\u226518 years for PVR. Right ventricular (RV) voltage maps were acquired and PVS was performed from two different sites at baseline, and if non\u2010inducible under isoproterenol. Catheter and\/or surgical ablation was performed when patients were inducible or when slow conduction was present in anatomical isthmuses (AIs). Postablation PVS was undertaken to guide implantable cardioverter\u2010defibrillator (ICD) implantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Seventy\u2010seven patients (36.2\u2009\u00b1\u200914.3 years old, 71% male) were included. Eighteen were inducible. In 28 patients (17 inducible, 11 non\u2010inducible but with slow conduction) ablation was performed. Five had catheter ablation, surgical cryoablation in 9, both techniques in 14. ICDs were implanted in five patients. During a follow\u2010up of 74\u2009\u00b1\u200940 months, no sudden cardiac death occurred. Three patients experienced sustained VAs, all were inducible during the initial EP study. Two of them had an ICD (low ejection fraction for one and important risk factor for arrhythmia for the second). No VAs were reported in the non\u2010inducible group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Preoperative EPS can help identifying patients with rTOF at risk for VAs, providing an opportunity for targeted ablation and may improve decision\u2010making regarding ICD implantation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.15940","type":"journal-article","created":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T07:06:51Z","timestamp":1685084811000},"page":"1395-1404","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Electrophysiological study prior to planned pulmonary valve replacement in patients with repaired tetralogy of Fallot"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7702-7610","authenticated-orcid":false,"given":"Benjamin","family":"Bouyer","sequence":"first","affiliation":[{"name":"Department of Cardiac Pacing and Electrophysiology Bordeaux University Hospital (CHU) Bordeaux France"},{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zakaria","family":"Jalal","sequence":"additional","affiliation":[{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"},{"name":"Department of Congenital Heart Disease Bordeaux University Hospital (CHU) Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4350-1652","authenticated-orcid":false,"given":"F.","family":"Daniel Ramirez","sequence":"additional","affiliation":[{"name":"University of Ottawa Heart Institute Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Derval","sequence":"additional","affiliation":[{"name":"Department of Cardiac Pacing and Electrophysiology Bordeaux University Hospital (CHU) Bordeaux France"},{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Iriart","sequence":"additional","affiliation":[{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"},{"name":"Department of Congenital Heart Disease Bordeaux University Hospital (CHU) Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josselin","family":"Duchateau","sequence":"additional","affiliation":[{"name":"Department of Cardiac Pacing and Electrophysiology Bordeaux University Hospital (CHU) Bordeaux France"},{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Roubertie","sequence":"additional","affiliation":[{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"},{"name":"Department of Congenital Heart Disease Bordeaux University Hospital (CHU) Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadir","family":"Tafer","sequence":"additional","affiliation":[{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"},{"name":"Department of Congenital Heart Disease Bordeaux University Hospital (CHU) Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Tixier","sequence":"additional","affiliation":[{"name":"Department of Cardiac Pacing and Electrophysiology Bordeaux University Hospital (CHU) Bordeaux France"},{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Pambrun","sequence":"additional","affiliation":[{"name":"Department of Cardiac Pacing and Electrophysiology Bordeaux University Hospital (CHU) Bordeaux France"},{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghassen","family":"Cheniti","sequence":"additional","affiliation":[{"name":"Department of Cardiac Pacing and Electrophysiology Bordeaux University Hospital (CHU) Bordeaux France"},{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7735-4056","authenticated-orcid":false,"given":"Ciro","family":"Ascione","sequence":"additional","affiliation":[{"name":"Department of Cardiac Pacing and Electrophysiology Bordeaux University Hospital (CHU) Bordeaux France"},{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0890-4189","authenticated-orcid":false,"given":"Masaaki","family":"Yokoyama","sequence":"additional","affiliation":[{"name":"Department of Cardiac Pacing and Electrophysiology Bordeaux University Hospital (CHU) Bordeaux France"},{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Kowalewski","sequence":"additional","affiliation":[{"name":"Department of Cardiac Pacing and Electrophysiology Bordeaux University Hospital (CHU) Bordeaux France"},{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Buliard","sequence":"additional","affiliation":[{"name":"Department of Cardiac Pacing and Electrophysiology Bordeaux University Hospital (CHU) Bordeaux France"},{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00e9mi","family":"Chauvel","sequence":"additional","affiliation":[{"name":"Department of Cardiac Pacing and Electrophysiology Bordeaux University Hospital (CHU) Bordeaux France"},{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0950-2624","authenticated-orcid":false,"given":"Marine","family":"Arnaud","sequence":"additional","affiliation":[{"name":"Department of Cardiac Pacing and Electrophysiology Bordeaux University Hospital (CHU) Bordeaux France"},{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e9l\u00e8ze","family":"Hocini","sequence":"additional","affiliation":[{"name":"Department of Cardiac Pacing and Electrophysiology Bordeaux University Hospital (CHU) Bordeaux France"},{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Ha\u00efssaguerre","sequence":"additional","affiliation":[{"name":"Department of Cardiac Pacing and Electrophysiology Bordeaux University Hospital (CHU) Bordeaux France"},{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Ja\u00efs","sequence":"additional","affiliation":[{"name":"Department of Cardiac Pacing and Electrophysiology Bordeaux University Hospital (CHU) Bordeaux France"},{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hubert","family":"Cochet","sequence":"additional","affiliation":[{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"},{"name":"Department of Radiology Bordeaux University Hospital (CHU) Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Benoit","family":"Thambo","sequence":"additional","affiliation":[{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux France"},{"name":"Department of Congenital Heart Disease Bordeaux University Hospital (CHU) Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederic","family":"Sacher","sequence":"additional","affiliation":[{"name":"Department of Cardiac Pacing and Electrophysiology Bordeaux University Hospital (CHU) Bordeaux France"},{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute University of Bordeaux Bordeaux 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