{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T02:48:32Z","timestamp":1777603712705,"version":"3.51.4"},"reference-count":10,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T00:00:00Z","timestamp":1692230400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>We studied the impact of the use of three\u2010dimensional multidetector computed tomography (3D\u2010MDCT) and fluoroscopy fusion on percutaneous left atrial appendage occlusion (LAAO) procedures in relation to procedure time, contrast volume, fluoroscopy time, and total radiation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a single\u2010center, prospective, single\u2010blinded, randomized control trial. Patients meeting criteria for LAAO were randomized to undergo LAAO with the WATCHMAN FLX<jats:sup>TM<\/jats:sup>device with and without 3D\u2010MDCT\u2010fluoroscopy fusion guidance using a prespecified protocol using computed tomography angiography for WATCHMAN FLX<jats:sup>TM<\/jats:sup>sizing, moderate sedation, and intracardiac echocardiography for procedural guidance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 59 participants were randomly assigned to the fusion (<jats:italic>n<\/jats:italic>\u2009=\u200933) or no fusion (<jats:italic>n<\/jats:italic>\u2009=\u200926) groups. The median (interquartile range) age was 79 (75\u201383) years, 24 (41%) were female, and 55 (93%) were Caucasian. The median CHA<jats:sub>2<\/jats:sub>DS<jats:sub>2<\/jats:sub>VASc and HASBLED scores were 5 (4\u20136) and 3 (3\u20134), respectively. At the time of the study, 51 (53%) patients were on a direct acting oral anticoagulant. There were no significant differences between the fusion and no fusion groups in procedure time (52.4\u2009\u00b1\u200915.4 vs. 56.8\u2009\u00b1\u200919.5\u2009min,<jats:italic>p<\/jats:italic>\u2009=\u2009.36), mean contrast volume used (33.8\u2009\u00b1\u200912.0 vs. 29.6\u2009\u00b1\u200911.5\u2009mls,<jats:italic>p<\/jats:italic>\u2009=\u2009.19), mean fluoroscopy time (31.3\u2009\u00b1\u20099.9 vs. 28.9\u2009\u00b1\u20098.7\u2009min,<jats:italic>p<\/jats:italic>\u2009=\u2009.32), mean radiation dose (1177\u2009\u00b1\u2009969 vs. 1091\u2009\u00b1\u2009692\u2009mGy,<jats:italic>p<\/jats:italic>\u2009=\u2009.70), and radiation dose product curve (23.9\u2009\u00b1\u200920.5 vs. 35.0\u2009\u00b1\u200949.1\u2009Gy\u2009cm<jats:sup>2<\/jats:sup>,<jats:italic>p<\/jats:italic>\u2009=\u2009.29). There was no periprosthetic leak in the two groups in the immediate 1\u2010month postprocedure follow\u2010up periods.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There was no significant difference with and without 3D\u2010MDCT\u2010fluoroscopy fusion in procedure time, contrast volume use, radiation dose, and radiation dose product.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.16035","type":"journal-article","created":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T04:49:16Z","timestamp":1692420556000},"page":"2076-2083","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Efficacy of 3D\u2010multidetector computed tomography and fluoroscopy fusion for percutaneous left atrial appendage occlusion procedures"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0880-3006","authenticated-orcid":false,"given":"Herman A.","family":"Carneiro","sequence":"first","affiliation":[{"name":"Division of Cardiology Harrington Heart &amp; Vascular Institute, University Hospitals Cleveland Medical Center Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis A. P.","family":"Dallan","sequence":"additional","affiliation":[{"name":"Division of Cardiology Harrington Heart &amp; Vascular Institute, University Hospitals Cleveland Medical Center Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung\u2010Han","family":"Yoon","sequence":"additional","affiliation":[{"name":"Division of Cardiology Harrington Heart &amp; Vascular Institute, University Hospitals Cleveland Medical Center Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shilpkumar","family":"Arora","sequence":"additional","affiliation":[{"name":"Division of Cardiology Harrington Heart &amp; Vascular Institute, University Hospitals Cleveland Medical Center Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliana","family":"Knezevich","sequence":"additional","affiliation":[{"name":"Division of Cardiology Harrington Heart &amp; Vascular Institute, University Hospitals Cleveland Medical Center Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sojin","family":"Wass","sequence":"additional","affiliation":[{"name":"Division of Cardiology Harrington Heart &amp; Vascular Institute, University Hospitals Cleveland Medical Center Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tabitha","family":"Lobo","sequence":"additional","affiliation":[{"name":"Department of Medicine University Hospitals Cleveland Medical Center Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauricio","family":"Arruda","sequence":"additional","affiliation":[{"name":"Division of Cardiology Harrington Heart &amp; Vascular Institute, University Hospitals Cleveland Medical Center Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Imran","family":"Rashid","sequence":"additional","affiliation":[{"name":"Division of Cardiology Harrington Heart &amp; Vascular Institute, University Hospitals Cleveland Medical Center Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8364-1732","authenticated-orcid":false,"given":"Steven J.","family":"Filby","sequence":"additional","affiliation":[{"name":"Division of Cardiology Harrington Heart &amp; Vascular Institute, University Hospitals Cleveland Medical Center Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,8,17]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.96.9.3112"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.32.3.803"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.115.011273"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.9.1747"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euv069"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.26998"},{"issue":"11","key":"e_1_2_10_8_1","doi-asserted-by":"crossref","first-page":"851","DOI":"10.25270\/jic\/20.00706","article-title":"Left atrial appendage occlusion using cardiac CT angiography and intracardiac echocardiography: a prospective, single\u2010center study","volume":"33","author":"Filby SJ","year":"2021","journal-title":"J Invasive Cardiol"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2021.01.035"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jez286"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-018-0016-5"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.16035","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,26]],"date-time":"2024-10-26T11:42:24Z","timestamp":1729942944000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.16035"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,17]]},"references-count":10,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.1111\/jce.16035"],"URL":"https:\/\/doi.org\/10.1111\/jce.16035","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,17]]},"assertion":[{"value":"2023-05-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}