{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:50:50Z","timestamp":1773013850921,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T00:00:00Z","timestamp":1695600000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Earlier studies have shown a clear association between severity of human immunodeficiency virus (HIV) infection and incident atrial fibrillation (AF). We present the long\u2010term outcome of catheter ablation (CA) and electrophysiological characteristics in HIV+ AF patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study evaluated 1438 consecutive AF patients [31 (2.15%) with HIV and 1407 (97.8%) without HIV diagnosis] undergoing their first CA at our center. A total of 31 HIV patients and 31 controls were generated by propensity matching, based on calculated risk factor scores, using a logistic model. During first procedure, all received isolation of pulmonary vein (PV)\u2009+\u2009posterior wall and superior vena cava. Non\u2010PV triggers, defined as ectopic triggers originating from sites other than PVs, were identified at the redo ablation with high\u2010dose isoproterenol challenge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Clinical characteristics were not different between the groups. When compared to the control, by the end of 5 years after the first procedure, recurrence was significantly greater in HIV group [100% vs. 54%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001]. Among patients that underwent redo ablation non\u2010PV triggers were higher in HIV group [93.5% vs. 54%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001], and most frequently originated from the coronary sinus [67.7% vs. 45.2%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001] and left atrial appendage [41.9% vs. 25.8%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001]. After focal ablation of non\u2010PV trigger, no difference in arrhythmia recurrence between two groups [80.6% vs. 87.1%, <jats:italic>p<\/jats:italic>\u2009=\u2009.753] at 1\u2010year follow up was found.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our findings suggest that non\u2010PV triggers are highly prevalent in HIV+ AF patients resulting in higher rate of the mid\u2010 and long\u2010term arrhythmia recurrence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.16076","type":"journal-article","created":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T10:46:18Z","timestamp":1695638778000},"page":"2527-2534","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Catheter ablation approach and outcome in HIV+ patients with recurrent atrial fibrillation"],"prefix":"10.1111","volume":"34","author":[{"given":"Vincenzo Mirco","family":"La 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Hospital \u201cOspedali Riuniti,\u201d Marche Polytechnic University Ancona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bryan","family":"MacDonald","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology, St David's Medical Center Texas Cardiac Arrhythmia Institute Austin Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angel","family":"Mayedo","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology, St David's Medical Center Texas Cardiac Arrhythmia Institute Austin Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prem Geeta","family":"Torlapati","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology, St David's Medical Center Texas Cardiac Arrhythmia Institute Austin Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Bassiouny","sequence":"additional","affiliation":[{"name":"Department of 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