{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T17:18:28Z","timestamp":1790875108013,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T00:00:00Z","timestamp":1695859200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Pulmonary vein isolation (PVI) is a pivotal part of ablative therapy for atrial fibrillation (AF). Currently, there are multiple techniques available to realize PVI, including: manual\u2010guided cryoballoon (MAN\u2010CB), manual\u2010guided radiofrequency (MAN\u2010RF), and robotic magnetic navigation\u2010guided radiofrequency ablation (RMN\u2010RF). There is a lack of large prospective trials comparing contemporary RMN\u2010RF with the more conventional ablation techniques. This study prospectively compared three catheter ablation techniques as treatment of paroxysmal AF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This multicenter, prospective study included patients with paroxysmal AF who underwent their first ablation procedure. Procedural parameters (including procedural efficiency), complication rates, and freedom of AF during 12\u2010month follow\u2010up, were compared between three study groups which were defined by the utilized ablation technique.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 221 patients were included in this study. Total procedure time was significantly shorter in MAN\u2010CB (78\u2009\u00b1\u200921\u2009min) compared to MAN\u2010RF (115\u2009\u00b1\u200941\u2009min; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) and compared to RMN\u2010RF (129\u2009\u00b1\u200932\u2009min; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), whereas it was comparable between the two radiofrequency\u00a0(RF) groups (<jats:italic>p<\/jats:italic>\u2009=\u2009.062). A 3% complication rate was observed, which was comparable between all groups. At 12\u2010month follow\u2010up, AF recurrence was observed in 40 patients (19%) and was significantly lower in the robotic group (MAN\u2010CB 19 [24%], MAN\u2010RF 16 [23%], RMN\u2010RF 5 [8%] AF recurrences, <jats:italic>p<\/jats:italic>\u2009=\u2009.045) (multivariate hazard ratio of RMN\u2010RF on AF recurrence 0.32, 95%\u00a0confidence interval: 0.12\u20130.87, <jats:italic>p<\/jats:italic>\u2009=\u2009.026).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>RMN\u2010guided\u00a0PVI results in high freedom of AF in patients with paroxysmal AF, when compared to cryoablation and manual RF ablation. Cryoablation remains the most time\u2010efficient ablation technique, whereas RMN nowadays has comparable efficiency with manual RF ablation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.16081","type":"journal-article","created":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T09:07:52Z","timestamp":1695892072000},"page":"2472-2483","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Robotic magnetic navigation\u2010guided catheter ablation establishes highly effective pulmonary vein isolation in patients with paroxysmal atrial fibrillation when compared to conventional ablation techniques"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1582-5315","authenticated-orcid":false,"given":"Anna M. E.","family":"Noten","sequence":"first","affiliation":[{"name":"Department of Cardiology, Erasmus MC University Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Romanov","sequence":"additional","affiliation":[{"name":"E. Meshalkin National Medical Research Center of the Ministry of Health of the Russian Federation Novosibirsk Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koen","family":"De Schouwer","sequence":"additional","affiliation":[{"name":"Department of Cardiology Ziekenhuis Netwerk Antwerpen Antwerp Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir","family":"Beloborodov","sequence":"additional","affiliation":[{"name":"E. Meshalkin National Medical Research Center of the Ministry of Health of the Russian Federation Novosibirsk Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohit","family":"Bhagwandien","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Erasmus MC University Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark G.","family":"Hoogendijk","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Erasmus MC University Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Mikheenko","sequence":"additional","affiliation":[{"name":"E. Meshalkin National Medical Research Center of the Ministry of Health of the Russian Federation Novosibirsk Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sip","family":"Wijchers","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Erasmus MC University Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4520-2725","authenticated-orcid":false,"given":"Sing\u2010Chien","family":"Yap","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Erasmus MC University Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Schwagten","sequence":"additional","affiliation":[{"name":"Department of Cardiology Ziekenhuis Netwerk Antwerpen Antwerp Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamas","family":"Szili\u2010Torok","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Erasmus MC University Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,9,28]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa612"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.005119"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2013.05.063"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.92.7.1954"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp2023658"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2029980"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199809033391003"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1602014"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.016871"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000038704.84304.6F"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-015-0023-3"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2010.09.074"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12929"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.14231"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.4022\/jafib.2108"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2017.05.012"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2012.07.016"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hroo.2020.04.003"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.108.824789"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euu376"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.112.004549"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2016-309781"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.014092"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.2174\/1573403X10666141013122400"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joa.2016.01.007"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.119.007517"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-020-00879-8"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.14392"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.113.000922"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-017-0261-7"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2020.05.028"},{"issue":"1","key":"e_1_2_9_33_1","first-page":"11","article-title":"A novel, highly efficient and effective minimal\u2010invasive ablation strategy for remote magnetic navigation guided pulmonary vein isolation","volume":"1","author":"Noten AME","year":"2022","journal-title":"J\u00a0Atrial Fibrillation Electrophysiol. 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