{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T16:25:10Z","timestamp":1792686310737,"version":"4.5.0"},"reference-count":33,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T00:00:00Z","timestamp":1695859200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Pulsed field ablation (PFA) is a new ablation technology for atrial fibrillation (AF). Data regarding early recurrences of atrial tachyarrhythmia (ERAT) after PFA\u2010pulmonary vein isolation (PVI) are sparse.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive patients with symptomatic AF were enrolled to undergo PFA\u2010PVI. A dedicated catheter delivering bipolar energy (1.9\u20132.0\u2009kV) was used. Late recurrence (LR) was defined as documented AF\/atrial tachycardia (AT) lasting more than 30\u2009s after a 90\u2010day blanking period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two hundred and thirty\u2010one patients (42% female, age 69\u2009\u00b1\u200912, 55% paroxysmal AF [PAF]) were included in this analysis. Median follow\u2010up time was 367 days (interquartile range: 253\u2013400). Forty\u2010six patients (21%) experienced ERAT after a median of 23 days (46% in PAF and 54% in persistent AF [persAF]). Kaplan\u2013Meier estimated freedom of AF\/AT was 74.2% at 1 year, 81.8% for PAF, and 64.8% for persAF (<jats:italic>p<\/jats:italic>\u2009=\u2009.0079). Of patients experiencing ERAT, an LR was observed in 54%. There was no significant difference of LR between those who presented with very early ERAT (0\u201345 days) and those with ERAT (46\u201390 days) (<jats:italic>p<\/jats:italic>\u2009=\u2009.57). In multivariate analysis, ERAT (hazard ratio [HR]: 3.370; 95% confidence interval [95% CI]: 1.851\u20136.136; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) and female sex (HR: 2.048; 95% CI: 1.114\u20133.768; <jats:italic>p<\/jats:italic>\u2009=\u2009.021) were the only independent predictors for LR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>ERAT could be recorded in 21% of patients after PFA\u2010PVI and was an independent predictor for LR. We found no difference in the rate of LRs among patients experiencing ERAT before or after 45 days.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.16083","type":"journal-article","created":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T08:58:03Z","timestamp":1695891483000},"page":"2425-2433","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Early recurrences predict late therapy failure after pulsed field ablation of atrial fibrillation"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-3931-8652","authenticated-orcid":false,"given":"Karin","family":"Plank","sequence":"first","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien CCB at Agaplesion Markus Krankenhaus Medizinische Klinik III Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0282-4658","authenticated-orcid":false,"given":"Stefano","family":"Bordignon","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien CCB at Agaplesion Markus Krankenhaus Medizinische Klinik III Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5234-744X","authenticated-orcid":false,"given":"Lukas","family":"Urbanek","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien CCB at Agaplesion Markus Krankenhaus Medizinische Klinik III Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaojie","family":"Chen","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien CCB at Agaplesion Markus Krankenhaus Medizinische Klinik III Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shota","family":"Tohoku","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien CCB at Agaplesion Markus Krankenhaus Medizinische Klinik III Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Schaack","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien CCB at Agaplesion Markus Krankenhaus Medizinische Klinik III Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Hirokami","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien CCB at Agaplesion Markus Krankenhaus Medizinische Klinik III Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tolga","family":"Efe","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien CCB at Agaplesion Markus Krankenhaus Medizinische Klinik III Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.R. 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