{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T05:27:15Z","timestamp":1790573235584,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T00:00:00Z","timestamp":1697500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The newly introduced nonthermal pulsed field ablation (PFA) is a promising technology to achieve fast pulmonary vein isolation (PVI) with high acute success rates and good safety features. However, previous studies have shown that very high power short duration ablation (VHPSD) is also highly effective and fast to achieve PVI with potentially less arrhythmia recurrence compared to conventional radiofrequency ablation. Data comparing PFA to VHPSD\u2010PVI is lacking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study compared procedural and outcome data for PFA\u2010PVI to VHPSD\u2010PVI in patients with paroxysmal or persistent atrial fibrillation (PAF\/persAF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Consecutive patients undergoing de novo PVI (PFA or VHPSD) were included in this analysis. For PFA\u2010PVI a pentaspline 20 electrode catheter was used. For VHPSD\u2010PVI an enhanced irrigated catheter with a power setting of 70\u2009W\/7\u2009s (70\u2009W\/5\u2009s at posterior wall) was employed in conjunction with electro\u2010anatomical mapping. All procedures were performed in deep analgo\u2010sedation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009114 patients (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200957[50%] PFA,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200917[30%] PAF;\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200940[70%] persAF) were included in this analysis. PVI was successful in all patients. The PFA group revealed a significantly shorter procedure duration (65\u2009\u00b1\u200917\u2009min vs. 95\u2009\u00b1\u200923\u2009min,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01) but longer fluoroscopy time (PFA 15\u2009\u00b1\u20095\u2009min and VHPSD 12\u2009\u00b1\u20093\u2009min;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). At follow\u2010up after median 125 days (interquartile range: 109\u2013162)\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200946 PFA (80.7%) and n\u2009=\u200944 VHPSD pts (77.2%) were free from atrial arrhythmia after a single procedure (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.819).\n                    <\/jats:p>\n                    <jats:p>Two tamponades occurred in the PFA while in VHPSD two pts suffered groin bleedings. One clinically nonsignificant PV stenosis occurred in the VHPSD group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Pulsed\u2010field ablation and VHPSD\u2010PVI seem to be highly effective and safe to achieve PVI in the setting of PAF and persAF with comparable arrhythmia\u2010free survival. However, procedure duration for PFA PVI is significantly shorter and therefore may be of potential benefit. Compared to PFA VHPSD\u2010PVI might ensure information on left atrial substrate allowing to target concomitant secondary tachycardias.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.16101","type":"journal-article","created":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T03:26:57Z","timestamp":1697513217000},"page":"2417-2424","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Comparison of pulsed\u2010field ablation versus very high power short duration\u2010ablation for pulmonary vein isolation"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2213-8946","authenticated-orcid":false,"given":"Jonas","family":"W\u00f6rmann","sequence":"first","affiliation":[{"name":"Department of Electrophysiology, Heart Center University of Cologne K\u00f6ln 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