{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T23:36:04Z","timestamp":1793144164986,"version":"4.5.0"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,11,14]],"date-time":"2023-11-14T00:00:00Z","timestamp":1699920000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Implant procedure features and clinical implications of left bundle branch pacing (LBBP) and left ventricular septal pacing (LVSP) have not been yet fully described. We sought to compare two different left bundle branch area pacing (LBBAP) implant strategies: the first one accepting LVSP as a procedural endpoint and the second one aiming at achieving LBBP in every patient in spite of evidence of previous LVSP criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      LVSP was accepted as a procedural endpoint in 162 consecutive patients (LVSP strategy group). In a second phase, LBBP was attempted in every patient in spite of achieving previous LVSP criteria (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009161, LBBP strategy group). Baseline patient characteristics, implant procedure, and follow\u2010up data were compared.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The final capture pattern was LBBP in 71.4% and LVSP in 24.2% in the LBBP strategy group compared to 42.7% and 50%, respectively, in the LVSP strategy group. One hundred and eighty\u2010four patients (57%) had proven LBB capture criteria with a significantly shorter paced QRS duration than the 120 patients (37%) with LVSP criteria (115\u2009\u00b1\u20099 vs. 121\u2009\u00b1\u200913\u2009ms,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001). Implant parameters were comparable between the two strategies but the LBBP strategy resulted in a higher rate of acute septal perforation (11.8% vs. 4.9%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.026) without any clinical sequelae. Patients with CRT indications significantly improved left ventricular ejection fraction (LVEF) during follow\u2010up irrespective of the capture pattern (from 35\u2009\u00b1\u200911% to 45\u2009\u00b1\u200914% in proven LBBP,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.024; and from 39\u2009\u00b1\u200913% to 47\u2009\u00b1\u200912% for LVSP,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.003). The presence of structural heart disease and baseline LBBB independently predicted unsuccessful LBB capture.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The LBBP strategy was associated with comparable implant parameters than the LVSP strategy but resulted in higher rates of septal perforation. Proven LBB capture and LVSP showed comparable effects on LVEF during follow\u2010up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.16128","type":"journal-article","created":{"date-parts":[[2023,11,14]],"date-time":"2023-11-14T07:20:03Z","timestamp":1699946403000},"page":"120-129","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Left bundle branch pacing versus left ventricular septal pacing as a primary procedural endpoint during left bundle branch area pacing: Evaluation of two different implant strategies"],"prefix":"10.1111","volume":"35","author":[{"given":"\u00d3scar","family":"Cano","sequence":"first","affiliation":[{"name":"Electrophysiology Section, Cardiology Department Hospital Universitari i Polit\u00e8cnic La Fe Valencia Spain"},{"name":"Centro de Investigaciones Biom\u00e9dicas en RED en Enfermedades Cardiovasculares (CIBERCV)  Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria La Fe Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Jover","sequence":"additional","affiliation":[{"name":"Electrophysiology Section, Cardiology Department Hospital Universitari i Polit\u00e8cnic La Fe Valencia Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria La Fe Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hebert D.","family":"Ayala","sequence":"additional","affiliation":[{"name":"Electrophysiology Section, Cardiology Department Hospital Universitari i Polit\u00e8cnic La Fe Valencia Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria La Fe Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Navarrete\u2010Navarro","sequence":"additional","affiliation":[{"name":"Electrophysiology Section, Cardiology Department Hospital Universitari i Polit\u00e8cnic La Fe Valencia Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria La Fe Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaqu\u00edn","family":"Osca","sequence":"additional","affiliation":[{"name":"Electrophysiology Section, Cardiology Department Hospital Universitari i Polit\u00e8cnic La Fe Valencia Spain"},{"name":"Centro de Investigaciones Biom\u00e9dicas en RED en Enfermedades Cardiovasculares (CIBERCV)  Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria La Fe Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maite","family":"Izquierdo","sequence":"additional","affiliation":[{"name":"Electrophysiology Section, Cardiology Department Hospital Universitari i Polit\u00e8cnic La Fe Valencia Spain"},{"name":"Centro de Investigaciones Biom\u00e9dicas en RED en Enfermedades Cardiovasculares (CIBERCV)  Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria La Fe Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep","family":"Navarro","sequence":"additional","affiliation":[{"name":"Electrophysiology Section, Cardiology Department Hospital Universitari i Polit\u00e8cnic La Fe Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Mart\u00ednez\u2010Dolz","sequence":"additional","affiliation":[{"name":"Electrophysiology Section, Cardiology Department Hospital Universitari i Polit\u00e8cnic La Fe Valencia Spain"},{"name":"Centro de Investigaciones Biom\u00e9dicas en RED en Enfermedades Cardiovasculares (CIBERCV)  Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria La Fe Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,11,14]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euad043"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2019.04.008"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.02.048"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2021.08.033"},{"key":"e_1_2_8_5_2","doi-asserted-by":"crossref","unstructured":"Erratum in:Heart Rhythm.2023.doi:10.1016\/j.hrthm.2021.08.033","DOI":"10.1016\/j.hrthm.2021.08.033"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2021.02.021"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euab164"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2019.06.016"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2019.05.011"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2017.09.013"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.115.003344"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2020.08.015"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hroo.2022.05.004"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2022.04.023"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehac445"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2017.10.039"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euac276"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2021.04.025"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.787414"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2023.1140988"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.16128","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,19]],"date-time":"2024-01-19T03:06:27Z","timestamp":1705633587000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.16128"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,14]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1111\/jce.16128"],"URL":"https:\/\/doi.org\/10.1111\/jce.16128","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,14]]},"assertion":[{"value":"2023-08-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}