{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T09:52:39Z","timestamp":1791280359184,"version":"4.1.0"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T00:00:00Z","timestamp":1707264000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Despite advancements in implantable cardioverter\u2010defibrillator (ICD) technology, sudden cardiac death (SCD) remains a persistent public health concern. Chagas disease (ChD), prevalent in Brazil, is associated with increased ventricular tachycardia (VT) and ventricular fibrillation (VF) events and SCD compared to other cardiomyopathies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective observational study included patients who received ICDs between October 2007 and December 2018. The study aims to assess whether mortality and VT\/VF events decreased in patients who received ICDs during different time periods (2007\u20132010, 2011\u20132014, and 2015\u20132018). Additionally, it seeks to compare the prognosis of ChD patients with non\u2010ChD patients. Time periods were chosen based on the establishment of the Arrhythmia Service in 2011. The primary outcome was overall mortality, assessed across the entire sample and the three periods. Secondary outcomes included VT\/VF events and the combined outcome of death or VT\/VF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 885 patients included, 31% had ChD. Among them, 28% died, 14% had VT\/VF events, and 37% experienced death and\/or VT\/VF. Analysis revealed that period 3 (2015\u20132018) was associated with better death\u2010free survival (<jats:italic>p<\/jats:italic>\u2009=\u2009.007). ChD was the only variable associated with a higher rate of VT\/VF events (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) and the combined outcome (<jats:italic>p<\/jats:italic>\u2009=\u2009.009).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Mortality and combined outcome rates decreased gradually for ICD patients during the periods 2011\u20132014 and 2015\u20132018 compared to the initial period (2007\u20132010). ChD was associated with higher VT\/VF events in ICD patients, only in the first two periods.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.16201","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T10:38:46Z","timestamp":1707302326000},"page":"675-684","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Evaluation of patients with implantable cardioverter\u2010defibrillator in a Latin American tertiary center"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-5363-1681","authenticated-orcid":false,"given":"Anna Terra","family":"Fran\u00e7a","sequence":"first","affiliation":[{"name":"Cardiology Service Hospital das Cl\u00ednicas da Universidade Federal de Minas Gerais Belo Horizonte Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larissa Natany 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