{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T20:20:35Z","timestamp":1791490835012,"version":"4.3.4"},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T00:00:00Z","timestamp":1709164800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Left bundle branch pacing (LBBP) is a physiological pacing modality. However, the long procedure and fluoroscopy time of LBBP is still a problem. This study aims to compare the clinical outcomes between transthoracic echocardiography (TTE)\u2010 and X\u2010ray\u2010guided LBBP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a single\u2010center, prospective, randomized controlled study. Consecutive patients who underwent LBBP in our team from June 2022 to November 2022 were enrolled. Procedure and fluoroscopy time, pacing parameters, electrophysiological and echocardiographic characteristics, as well as complications were recorded at implantation and during follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In this study, 60 patients were enrolled and divided into two groups: 30 patients were allocated to the X\u2010ray group and the remaining 30 to the TTE group. There was no significant difference in the success rate between the two groups (86.7% vs. 76.7%, <jats:italic>p<\/jats:italic>\u2009=\u2009.317). The procedure time of TTE group was comparable to that of the X\u2010ray group (9.0 vs. 12.0\u2009min, <jats:italic>p<\/jats:italic>\u2009=\u2009.063). However, the fluoroscopy time in the TTE group was significantly lower than that of the X\u2010ray group (2.5 vs. 5.0\u2009min, <jats:italic>p<\/jats:italic>\u2009=\u2009.002). There were no statistically significant differences in pacing parameters, electrophysiological and echocardiographic characteristics, or complications between the two groups at implantation and during follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>TTE\u2010guided LBBP is a feasible and safe method. Compared with X\u2010ray, TTE showed a comparable success rate and procedure time, but it could significantly reduce the fluoroscopy time of LBBP.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.16212","type":"journal-article","created":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T04:45:01Z","timestamp":1709268301000},"page":"875-882","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Comparison of clinical outcomes between transthoracic echocardiography\u2010 and X\u2010ray\u2010guided left bundle branch pacing for bradycardia: A randomized controlled trial"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-5097-2549","authenticated-orcid":false,"given":"Zhihan","family":"Yang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Cardiovascular Disease, Arrhythmia Center, Fuwai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences 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