{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:06:52Z","timestamp":1791216412521,"version":"4.1.0"},"reference-count":45,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,3,22]],"date-time":"2024-03-22T00:00:00Z","timestamp":1711065600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Limited data exist on pulsed\u2010field ablation (PFA) in patients with persistent atrial fibrillation (PeAF) undergoing left atrial posterior wall isolation (LAPWI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The Advanced TecHnologies For SuccEssful AblatioN of AF in Clinical Practice (ATHENA) prospective registry included consecutive patients referred for PeAF catheter ablation at 9 Italian centers, treated with the FARAPULSE\n                      <jats:sup>TM<\/jats:sup>\n                      \u2010PFA system. The primary efficacy and safety study endpoints were the acute LAPWI rate, freedom from arrhythmic recurrences and the incidence of major periprocedural complications. Patients undergoing pulmonary vein isolation (PVI) alone, PWI\u2009+\u2009LAPWI and redo procedures were compared.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 249 patients, 21.7% had long\u2010standing PeAF, 79.5% were male; mean age was 63\u2009\u00b1\u20099 years. LAPWI was performed in 57.6% of cases, with 15.3% being redo procedures. Median skin\u2010to\u2010skin times (PVI\u2010only 68 [60\u221290] vs. PVI\u2009+\u2009LAPWI 70 [59\u221288] mins) did not differ between groups. 45.8% LAPWI cases were approached with a 3D\u2010mapping system, and 37.3% with intracardiac echocardiography. LAPWI was achieved in all patients by means of PFA alone, in 88.8% cases at first pass. LAPWI was validated either by an Ultrahigh\u2010density mapping system or by recording electrical activity\u2009+\u2009pacing maneuvers. No major complications occurred, while 2.4% minor complications were detected. During a median follow\u2010up of 273 [191\u2013379] days, 41 patients (16.5%) experienced an arrhythmic recurrence after the 90\u2010day blanking period, with a mean time to recurrence of 223\u2009\u00b1\u2009100 days and no differences among ablation strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>LAPWI with PFA demonstrates feasibility, rapidity, and safety in real\u2010world practice, offering a viable alternative for PeAF patients. LAPWI is achievable even with a fluoroscopy\u2010only method and does not significantly extend overall procedural times.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.16246","type":"journal-article","created":{"date-parts":[[2024,3,22]],"date-time":"2024-03-22T23:10:50Z","timestamp":1711149050000},"page":"1101-1111","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Pulsed field ablation technology for pulmonary vein and left atrial posterior wall isolation in patients with persistent atrial fibrillation"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0720-3380","authenticated-orcid":false,"given":"Marco","family":"Schiavone","sequence":"first","affiliation":[{"name":"Department of Clinical Electrophysiology &amp; Cardiac Pacing Centro Cardiologico Monzino, IRCCS Milan Italy"},{"name":"Department of Systems Medicine University of Rome Tor Vergata Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Solimene","sequence":"additional","affiliation":[{"name":"Montevergine Clinic Mercogliano Avellino Italy"},{"name":"Department of Biomedical Sciences and Public Health Marche Polytechnic University Ancona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Moltrasio","sequence":"additional","affiliation":[{"name":"Department of Clinical Electrophysiology &amp; Cardiac Pacing Centro Cardiologico Monzino, IRCCS Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michela","family":"Casella","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Arrhythmology Clinic University Hospital Ospedali Riuniti Umberto I\u2010Lancisi\u2010Salesi Ancona Italy"},{"name":"Department of Clinical, Special and Dental Sciences Marche Polytechnic University Ancona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Bianchi","sequence":"additional","affiliation":[{"name":"Fatebenefratelli Isola Tiberina\u2014Gemelli Isola Hospital Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2131-1110","authenticated-orcid":false,"given":"Saverio","family":"Iacopino","sequence":"additional","affiliation":[{"name":"Maria Cecilia Hospital  Cotignola Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6043-0382","authenticated-orcid":false,"given":"Antonio","family":"Rossillo","sequence":"additional","affiliation":[{"name":"San Bortolo Hospital Vicenza Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Schillaci","sequence":"additional","affiliation":[{"name":"Montevergine Clinic Mercogliano Avellino Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaetano","family":"Fassini","sequence":"additional","affiliation":[{"name":"Department of Clinical Electrophysiology &amp; Cardiac Pacing Centro Cardiologico Monzino, IRCCS Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1924-6548","authenticated-orcid":false,"given":"Paolo","family":"Compagnucci","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences and Public Health Marche Polytechnic University Ancona Italy"},{"name":"Department of Cardiology and Arrhythmology Clinic University Hospital Ospedali Riuniti Umberto I\u2010Lancisi\u2010Salesi Ancona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armando","family":"Salito","sequence":"additional","affiliation":[{"name":"Montevergine Clinic Mercogliano Avellino Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Rossi","sequence":"additional","affiliation":[{"name":"Fatebenefratelli Isola Tiberina\u2014Gemelli Isola Hospital Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pasquale","family":"Filannino","sequence":"additional","affiliation":[{"name":"Maria Cecilia Hospital  Cotignola Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruggero","family":"Maggio","sequence":"additional","affiliation":[{"name":"Degli Infermi Hospital Rivoli Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sakis","family":"Themistoklakis","sequence":"additional","affiliation":[{"name":"Dell'Angelo Hospital Mestre Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5476-4124","authenticated-orcid":false,"given":"Claudio","family":"Pandozi","sequence":"additional","affiliation":[{"name":"San Filippo Neri Hospital Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Caprioglio","sequence":"additional","affiliation":[{"name":"San Bortolo Hospital Vicenza Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8823-0334","authenticated-orcid":false,"given":"Maurizio","family":"Malacrida","sequence":"additional","affiliation":[{"name":"Boston Scientific Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio Dello","family":"Russo","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences and Public Health Marche Polytechnic University Ancona Italy"},{"name":"Department of Cardiology and Arrhythmology Clinic University Hospital Ospedali Riuniti Umberto I\u2010Lancisi\u2010Salesi Ancona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Tondo","sequence":"additional","affiliation":[{"name":"Department of Clinical Electrophysiology &amp; Cardiac Pacing Centro Cardiologico Monzino, IRCCS Milan Italy"},{"name":"Department of Biomedical, Surgical and Dental Sciences University of Milan Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,3,22]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa612"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.23722"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.108.797944"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.15164"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-023-01549-1"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2023.01.014"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.118.007005"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.14480"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euaa278"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehad250"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2018.10.030"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2018.04.005"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.04.021"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euac050"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euad185"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euac041"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euac044"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.14647"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.985182"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-023-01655-0"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2023.1169037"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.14220"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2017.05.012"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2015.08.019"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-019-00634-8"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.5282"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2022.02.001"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2020.05.005"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2020.11.008"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.07.007"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.15349"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.14823"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12196304"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2307291"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euab085"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hjc.2022.03.006"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2010.07.004"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2023.08.018"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.119.007781"},{"key":"e_1_2_9_41_1","article-title":"Impact of left atrial posterior wall ablation during pulsed field ablation for persistent atrial fibrillation","author":"Turagam MK","year":"2024","journal-title":"Epublished"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2022.11.007"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2023.01.014"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.123.063988"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-023-01728-0"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euad257"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.16246","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T00:33:25Z","timestamp":1720485205000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.16246"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,22]]},"references-count":45,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1111\/jce.16246"],"URL":"https:\/\/doi.org\/10.1111\/jce.16246","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,22]]},"assertion":[{"value":"2023-12-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}