{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T16:01:11Z","timestamp":1792598471220,"version":"4.5.0"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,4,3]],"date-time":"2024-04-03T00:00:00Z","timestamp":1712102400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Left atrial (LA) low voltage areas (LVA) are a controversial target in atrial fibrillation ablation procedures. However, LVA and LA volume are good predictors of arrhythmia recurrence in ablation\u2010na\u00efve patients. Their predictive value in progressively diseased pre\u2010ablated atria is uncertain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Consecutive patients with recurrent atrial fibrillation (AF) or atrial tachycardia (AT), who were scheduled for repeat LA ablation, were enrolled in the prospective Bernau ablation registry between 2016 and 2020. All patients received a complete LA ultrahigh\u2010density map before ablation. Maps were analyzed for LA size, LVA percentage and distribution. The predictive value of demographic, anatomic, and mapping variables on AF recurrence was analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      160 patients (50.6% male, 1.3 pre\u2010ablations, 60% persistent AF) with complete LA voltage maps were included. Mean follow\u2010up time was 16\u2009\u00b1\u200911 months. Mean recorded electrograms (EGMs) per map were 9754\u2009\u00b1\u20095808, mean LA volume was 176.1\u2009\u00b1\u200935.9\u2009ml and mean rate of LVAs &lt;0.5\u2009mV was 30.6%\u2009\u00b1\u200923.1%. During follow\u2010up recurrence rate of AF or AT\u00a0&gt;30\u2009s was 55.6%. Patients with recurrence had a significant higher percentage of LVAs (40.0% vs. 18.8%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001) but no relevant difference in LA volume (172 vs. 178\u2009mL,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.299). ROC curves revealed LVA as a good predictor for recurrence (AUC\u2009=\u20090.79,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001) and a cut\u2010off of 22% LVAs with highest sensitivity (73.0%) and specificity (71.8%). Based on this cut off, event free survival was significantly higher in the Low LVA group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Total LVA percentage has a good predictive power on arrhythmia recurrence in a cohort of advanced scarred left atria in repeat procedures independent of the applied ablation strategy. Left atrial volume seems to have minor impact on the rhythm outcome in our study cohort.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.16266","type":"journal-article","created":{"date-parts":[[2024,4,3]],"date-time":"2024-04-03T03:38:26Z","timestamp":1712115506000},"page":"1156-1164","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Left atrial low\u2010voltage areas, but not volume, predict the recurrence of atrial fibrillation in repeat ablation procedures"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5991-2333","authenticated-orcid":false,"given":"Christian","family":"Georgi","sequence":"first","affiliation":[{"name":"Department of Cardiology, Brandenburg Medical School (MHB) Theodor Fontane University Hospital Heart Center Brandenburg Neuruppin 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Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"Haase\u2010Fielitz","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Brandenburg Medical School (MHB) Theodor Fontane University Hospital Heart Center Brandenburg Neuruppin Germany"},{"name":"Faculty of Health Sciences Brandenburg Neuruppin Germany"},{"name":"Institute of Social Medicine and Health System Research Otto von Guericke University Magdeburg Magdeburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Butter","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Brandenburg Medical School (MHB) Theodor Fontane University Hospital Heart Center Brandenburg Neuruppin Germany"},{"name":"Faculty of Health Sciences Brandenburg Neuruppin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Seifert","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Brandenburg Medical School (MHB) Theodor Fontane University Hospital Heart Center Brandenburg Neuruppin Germany"},{"name":"Faculty of Health Sciences Brandenburg Neuruppin 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