{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T02:03:06Z","timestamp":1776996186310,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T00:00:00Z","timestamp":1712534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The left ventricular summit (LVS) is the highest point on the epicardial surface of the left ventricle. A part of the LVS that is located between the left coronary arteries (lateral\u2010LVS) is one of the major sites of idiopathic ventricular arrhythmia (VA) origins. Some idiopathic epicardial VAs can be ablated at endocardial sites adjacent to the epicardial area septal to the lateral\u2010LVS (septal\u2010LVS). This study examined the prevalence and electrocardiographic and electrophysiological characteristics of septal\u2010LVS VAs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We studied consecutive patients with idiopathic VAs originating from the LVS (67 patients) and aortic root (93 patients).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Based on the ablation results, among 67 LVS VAs, 54 were classified as lateral and 13 as septal\u2010LVS VAs. As compared with the lateral\u2010LVS VAs, the septal\u2010LVS VAs were characterized by a greater prevalence of left bundle branch block with left inferior\u2010axis QRS pattern, later precordial transition, lower R\u2010wave amplitude ratio in leads III to II, lower Q\u2010wave amplitude ratio in leads aVL to aVR, and later local ventricular activation time relative to the QRS onset during VAs (V\u2010QRS) in the great cardiac vein. The electrocardiographic and electrophysiological characteristics of the septal\u2010LVS VAs were similar to those of the aortic root VAs. However, the V\u2010QRS at the successful ablation site was significantly later during the septal\u2010LVS VAs than aortic root VAs (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.0001). The precordial transition was significantly later during the septal\u2010LVS VAs than aortic root VAs (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Septal\u2010LVS VAs are considered a distinct subgroup of idiopathic VAs originating from the left ventricular outflow tract.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.16270","type":"journal-article","created":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T12:09:01Z","timestamp":1712578141000},"page":"1174-1184","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Prevalence and electrocardiographic and electrophysiological characteristics of idiopathic ventricular arrhythmias originating from the septal left ventricular 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