{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T04:54:22Z","timestamp":1784609662630,"version":"3.55.0"},"reference-count":26,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,5,27]],"date-time":"2024-05-27T00:00:00Z","timestamp":1716768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Mitral annular flutter (MAF) is the most common left atrial macro\u2010reentrant arrhythmia following catheter ablation of atrial fibrillation (AF). The best ablation approach for this arrhythmia remains unclear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This single\u2010center, retrospective study sought to compare the acute and long\u2010term outcomes of patients with MAF treated with an anterior mitral line (AML) versus a mitral isthmus line (MIL). Acute ablation success, complication rates, and long\u2010term arrhythmia recurrence were compared between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Between 2015 and 2021, a total of 81 patients underwent ablation of MAF (58 with an AML and 23 with a MIL). Acute procedural success defined as bidirectional block was achieved in 88% of the AML and 91% of the MIL patients respectively (<jats:italic>p<\/jats:italic>\u2009=\u20091.0). One year freedom from atrial arrhythmias was 49.5% versus 77.5% and at 4 years was 24% versus 59.6% for AML versus MIL, respectively (hazard ratio [HR]: 0.38, confidence interval [CI]: 0.17\u20130.82, <jats:italic>p<\/jats:italic>\u2009=\u2009.009). Fewer patients in the MIL group had recurrent atrial flutter when compared to the AML group (HR: 0.32, CI: 0.12\u20130.83, <jats:italic>p<\/jats:italic>\u2009=\u2009.009). The incidence of recurrent AF, on the other side, was not different between both groups (21.7% vs. 18.9%; <jats:italic>p<\/jats:italic>\u2009=\u2009.76). There were no serious adverse events in either group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this retrospective study of patients with MAF, a MIL compared to AML was associated with a long\u2010term reduction in recurrent atrial arrhythmias driven by a reduction in macroreentrant atrial flutters.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.16325","type":"journal-article","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T03:39:25Z","timestamp":1716867565000},"page":"1480-1486","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Comparison of anterior mitral line and mitral isthmus line for ablation of mitral annular flutter"],"prefix":"10.1111","volume":"35","author":[{"given":"Victor","family":"Neira","sequence":"first","affiliation":[{"name":"Division of Cardiology Queen's University Kingston Ontario 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