{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T03:26:53Z","timestamp":1782790013355,"version":"3.54.5"},"reference-count":13,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,6,30]],"date-time":"2024-06-30T00:00:00Z","timestamp":1719705600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The use of CRT\u2010D devices with left ventricular (LV) sensing has created controversy about programming various parameters especially the left ventricular T wave protection (LVTP) designed to prevent the delivery of a pacing stimulus into the LV vulnerable period. Such devices are available from two manufacturers. This review focuses only on those provided by Biotronik. As the LVTP controls LV sensing, some investigators have advocated turning off the LVTP to prevent episodic desynchronization known a CRT pacing interrupt. However, LVTP off reduces but does not eliminate this type of desynchronization if triggering of an LV stimulus upon right ventricular sensing (RVs) is programmed on. Deactivation of the LVTP incurs loss of diagnostic data provided by CRT pacing interrupt itself. By choice, the occurrence of CRT pacing interrupt can be totally eliminated by appropriate programming of the LV upper rate interval, LVTP and triggering of an LV pacing event upon RVs. Various programmability options are available according to clinical circumstances. As a rule, clinical judgement must weigh the potential diagnostic benefit of preserving the LVTP capable of recording of episodic CRT pacing interrupt against the loss of diagnostic benefit when LVTP is programmed off (with or without triggering of an LV stimulus upon RVs).<\/jats:p>","DOI":"10.1111\/jce.16340","type":"journal-article","created":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T04:33:35Z","timestamp":1719808415000},"page":"1863-1870","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Clinical use of CRT\u2010D devices with left ventricular sensing: Impact of the desynchronization\u2010detection algorithm"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4951-6465","authenticated-orcid":false,"given":"S. Serge","family":"Barold","sequence":"first","affiliation":[{"name":"University of Rochester School of Medicine and Dentistry Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9233-0503","authenticated-orcid":false,"given":"Andreas","family":"Kucher","sequence":"additional","affiliation":[{"name":"BIOTRONIK SE &amp; Co. KG Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,30]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.13744"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.14039"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.13883"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.14574"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2020.02.007"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.13677"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/anec.12473"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2018.01.003"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/joa3.12207"},{"key":"e_1_2_4_11_1","unstructured":"BostonScientific 2009 Left ventricular protection period (LVPP) during left ventricular threshold testing"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2017.10.012"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.15798"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.14851"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.16340","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T11:52:21Z","timestamp":1732017141000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.16340"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,30]]},"references-count":13,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["10.1111\/jce.16340"],"URL":"https:\/\/doi.org\/10.1111\/jce.16340","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,30]]},"assertion":[{"value":"2024-02-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}