{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T18:24:11Z","timestamp":1791397451904,"version":"4.3.3"},"reference-count":31,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,7,14]],"date-time":"2024-07-14T00:00:00Z","timestamp":1720915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007497","name":"Biosense Webster","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007497","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The VARIPULSE\u2122 variable\u2010loop circular catheter (VLCC) is a bidirectional, multielectrode catheter that can perform electrophysiological mapping and deliver pulsed field energy through the TRUPULSE\u2122 Generator for the treatment of atrial fibrillation. This ablation system, including the CARTO 3\u2122 three\u2010dimensional electroanatomical mapping system, represents a fully integrated system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Pulsed field ablation (PFA) is a novel, primarily cardiac tissue\u2013selective ablation technology with a minimal thermal effect, potentially eliminating the collateral tissue damage associated with radiofrequency ablation or cryoablation. Integration of a mapping system may lead to shorter fluoroscopy times and improve the usability of the system, allowing tracking of energy density and placement to confirm no areas around the vein are left untreated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>This step\u2010by\u2010step review covers patient selection, mapping, the step\u2010by\u2010step ablation workflow, details on catheter repositioning and ensuring contact, considerations for ablation of specific anatomical variations, and discussion of ablation without fluoroscopy based on our initial clinical experience.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The VLCC is part of the fully integrated PFA system designed for pulmonary vein isolation, using mapping to guide catheter placement and lesion set creation. The current workflow, which is based on our initial clinical experience, may be further refined as the PFA system is used in real\u2010world settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.16366","type":"journal-article","created":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T00:20:02Z","timestamp":1721002802000},"page":"1817-1827","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["VARIPULSE: A step\u2010by\u2010step guide to pulmonary vein isolation"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8253-947X","authenticated-orcid":false,"given":"Devi G.","family":"Nair","sequence":"first","affiliation":[{"name":"Electrophysiology Division St. Bernards Healthcare Jonesboro Arkansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tara","family":"Gomez","sequence":"additional","affiliation":[{"name":"Medical Affairs Biosense Webster, Inc. Irvine California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1424-114X","authenticated-orcid":false,"given":"Tom","family":"De Potter","sequence":"additional","affiliation":[{"name":"OLV Hospital, Dienst Cardiologie Aalst Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,14]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa612"},{"issue":"149","key":"e_1_2_14_3_1","first-page":"e1","article-title":"ACC\/AHA\/ACCP\/HRS guideline for the diagnosis and management of atrial fibrillation: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"2024","author":"Joglar JA","year":"2023","journal-title":"Circulation"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euae043"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jviscsurg.2023.08.003"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehad250"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.122.011780"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.15522"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.119.007781"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.119.008192"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2021.02.014"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.04.021"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2018.10.030"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.121.010168"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.120.009229"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.120.008580"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.121.010661"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hroo.2023.09.005"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.123.012667"},{"key":"e_1_2_14_20_1","unstructured":"ReddyVY CalkinsH MansourM et al. Long\u2010term safety and effectiveness after paroxysmal atrial fibrillation pulsed field ablation from the U.S. multicenter AdmIRE study presented at: the Heart Rhythm Society Annual Meeting.2024. May 16\u201019;Boston MA."},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.121.010375"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-022-01445-0"},{"key":"e_1_2_14_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euad222"},{"key":"e_1_2_14_24_1","unstructured":"Clinicaltrials.gov. NCT05293639. Assessment of safety and effectiveness in treatment management of atrial fibrillation with the BWI IRE ablation system. 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