{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T22:03:33Z","timestamp":1790373813674,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,11,3]],"date-time":"2024-11-03T00:00:00Z","timestamp":1730592000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aims<\/jats:title><jats:p>Atrial fibrillation is the most prevalent cardiac arrhythmia, and catheter ablation (CA) has emerged as a viable treatment option for selected patients. However, its safety profile in liver cirrhosis (LC) populations remains underexplored.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was an observational analysis of the National Inpatient Sample Database 2016\u20132020; we analyzed adult encounters undergoing CA for atrial fibrillation who had a concomitant diagnosis of LC. Using propensity scores, encounters were divided into two cohorts based on the presence or absence of LC and matched in a 1:1 fashion using LC as the dependent variable. In\u2010hospital mortality and postprocedure total complications were compared using regression models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>93\u2009830 procedures were identified for non\u2010LC patients and 960 involving LC patients; after propensity score matching, each cohort included 910 hospitalizations. The mean age in the LC\u2010matched cohort was 66.5\u2009\u00b1\u20099.1 years. In\u2010hospital mortality did not differ between the groups (aOR\u2009=\u20091.01; 95% CI [0.06\u201316.1]; <jats:italic>p<\/jats:italic>\u2009=\u2009.99). However, the LC cohort exhibited higher odds of total complications (aOR\u2009=\u20091.98; 95% CI [1.42\u20132.75]; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). Length of stay (LOS) was comparable, but total costs were higher in the LC cohort: LOS was 2 days (95% CI [1\u20133]) in the LC group versus 3 days (95% CI [1\u20134]) (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.11) and LC: $202,000 (95% CI [$142\u2009000\u2013$261\u2009000]) versus non\u2010LC: $189\u2009000, (95% CI [$153\u2009000\u2013$222\u2009000]) (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this national analysis of patients undergoing CA for AF, those with LC had similar in\u2010hospital mortality, postprocedure complications, and LOS compared to noncirrhotic patients. Furthermore, longitudinal studies are needed to assess the safety profile of CA in this subpopulation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.16472","type":"journal-article","created":{"date-parts":[[2024,11,4]],"date-time":"2024-11-04T04:18:48Z","timestamp":1730693928000},"page":"103-110","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Safety of catheter ablation for atrial fibrillation in patients with liver cirrhosis"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8031-0601","authenticated-orcid":false,"given":"Nelson","family":"Barrera","sequence":"first","affiliation":[{"name":"Montefiore\u2010Einstein Center for Heart and Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine Bronx New York USA"},{"name":"SBH Health System, Department of Internal Medicine City University of New York School of Medicine Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katerina","family":"Jou","sequence":"additional","affiliation":[{"name":"SBH Health System, Department of Internal Medicine City University of New York School of Medicine Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mushrin","family":"Malik","sequence":"additional","affiliation":[{"name":"SBH Health System, Department of Internal Medicine City University of New York School of Medicine Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Gallegos\u2010Koyner","sequence":"additional","affiliation":[{"name":"SBH Health System, Department of Internal Medicine City University of New York School of Medicine Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salomon","family":"Chamay","sequence":"additional","affiliation":[{"name":"SBH Health System, Department of Internal Medicine City University of New York School of Medicine Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled","family":"Elfert","sequence":"additional","affiliation":[{"name":"SBH Health System, Department of Internal Medicine City University of New York School of Medicine Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8417-2456","authenticated-orcid":false,"given":"Roberto C.","family":"Cerrud\u2010Rodriguez","sequence":"additional","affiliation":[{"name":"Section of Cardiovascular Medicine, Yale New Haven Hospital Yale University New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6508-4047","authenticated-orcid":false,"given":"Luigi","family":"Di Biase","sequence":"additional","affiliation":[{"name":"Montefiore\u2010Einstein Center for Heart and Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2023.08.017"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp2023658"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0000000000001315"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.21037\/atm-21-3111"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.4330\/wjc.v12.i7.342"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.118.008703"},{"issue":"6","key":"e_1_2_9_8_1","first-page":"557","article-title":"Anticoagulation in patients with atrial fibrillation and liver cirrhosis","volume":"35","author":"Karapedi E","year":"2022","journal-title":"Ann Gastroenterol"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2022.05.030"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.704073"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.116.005307"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.122.058575"},{"key":"e_1_2_9_13_1","unstructured":"Healthcare Af Quality Ra. 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