{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T05:22:11Z","timestamp":1736832131335,"version":"3.33.0"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,11,18]],"date-time":"2024-11-18T00:00:00Z","timestamp":1731888000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Brugada syndrome (BS) is a genetic channelopathy characterized by an increased risk of sudden cardiac death (SCD) in the absence of structural heart disease. Prognostic stratification is necessary to determine which patients are candidates for implantable cardioverter defibrillator (ICD). The present study aims to evaluate EKG changes during exercise stress tests in patients with BS and to identify any poor prognosis variables.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was an observational, case\u2010control study. Three comparison groups were created: patients with Type 1 BS with or without prior arrhythmic events (BE and BNoE subgroups) and age\u2010 and sex\u2010matched healthy individuals. Patients underwent EST and electrocardiographic variables were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study recruited 36 patients with type 1 BS, 12 with prior Event (BE) and 24 without (BNoE). Patients in the BE group, in all postexercise recordings, had lower heart rates, notably in the first minute. A significant difference was also observed in the HR drop in the recovery phase, with a greater drop in relation to maximum HR in the first minute in the group of patients who had events.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>BS patients with prior events had a lower capacity to increase heart rate at peak effort and a greater proportional drop in the recovery phase. No relationship was observed between the occurrence of arrhythmic events and ST\u2010segment elevation during the exercise test.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.16494","type":"journal-article","created":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T05:09:44Z","timestamp":1731992984000},"page":"212-219","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Electrocardiographic Characteristics of Brugada Syndrome Type I During Exercise Stress Test"],"prefix":"10.1111","volume":"36","author":[{"given":"Camila Pinto Cavalcante","family":"Min\u00e1","sequence":"first","affiliation":[{"name":"Postgraduate Program in Cardiovascular Sciences Federal University of Ceara Fortaleza Ceara Brazil"},{"name":"Hospital do Coracao de Messejana Dr Carlos Alberto Studart Gomes Fortaleza Ceara Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neiberg de Alcantara","family":"Lima","sequence":"additional","affiliation":[{"name":"Heart and Vascular Institute Hartford Hospital Hartford Connecticut USA"},{"name":"Department of Internal Medicine, Division of Cardiology Wayne State University Detroit Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio Thomaz","family":"de Andrade","sequence":"additional","affiliation":[{"name":"Hospital do Coracao de Messejana Dr Carlos Alberto Studart Gomes Fortaleza Ceara Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9s Ricardo","family":"P\u00e9rez\u2010Riera","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Nove de Julho University \u2013 UNINOVE Sao Paulo Sao Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo Arrais","family":"Rocha","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Cardiovascular Sciences Federal University of Ceara Fortaleza Ceara 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