{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T04:41:39Z","timestamp":1773981699221,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T00:00:00Z","timestamp":1733270400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Research on the impact of angiographically detected residual trabeculation after left atrial appendage closure (LAAC) is limited.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate the incidence, characteristics, and clinical implications of angiographically detected residual trabeculation after LAAC using the WATCHMAN device.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analyzed 1350 consecutive patients with atrial fibrillation undergoing LAAC using the WATCHMAN device from the OCEAN\u2010LAAC registry, which is a prospective ongoing, multicenter Japanese registry. The inclusion criteria comprised patients who successfully underwent LAAC and whose presence or absence of residual trabeculation can be confirmed using a contrast medium. The clinical outcomes were compared between patients with and without angiographically detected residual trabeculation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Residual trabeculation was angiographically detected in 5.6% (75\/1350 patients). At the procedure, the proportion of peri\u2010device leak (PDL) was significantly higher in the residual trabeculation group than in the non\u2010residual trabeculation group (20% vs. 5.1%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). However, the PDL and device\u2010related thrombosis at 45 days and 1 year were comparable between the two groups (37% vs. 23%, <jats:italic>p<\/jats:italic>\u2009=\u20090.24; 28% vs. 31%, <jats:italic>p<\/jats:italic>\u2009=\u20090.84; 2.1% vs. 1.4%, <jats:italic>p<\/jats:italic>\u2009=\u20090.50; 6.9% vs. 6.0%, <jats:italic>p<\/jats:italic>\u2009=\u20090.69, respectively). The 3\u2010year cumulative incidence of ischemic stroke, all cardiovascular death, and all\u2010cause death were comparable between the two groups (5.7% vs. 5.5%, log\u2010rank <jats:italic>p<\/jats:italic>\u2009=\u20090.96; 7.7% vs. 8.9%, log\u2010rank <jats:italic>p<\/jats:italic>\u2009=\u20090.34, 31.4% vs. 22.3%, log\u2010rank <jats:italic>p<\/jats:italic>\u2009=\u20090.71, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The angiographically detected residual trabeculation rate was 5.6%, and this population had a significantly higher prevalence of PDL at the procedure. However, the presence of residual trabeculation did not contribute to PDL or device\u2010related thrombosis at follow\u2010up or affect the clinical outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.16517","type":"journal-article","created":{"date-parts":[[2024,12,5]],"date-time":"2024-12-05T05:30:46Z","timestamp":1733376646000},"page":"347-358","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of Angiographically Detected Residual Trabeculation After Left Atrial Appendage Closure Using the WATCHMAN Device: Insight From the OCEAN\u2010LAAC Registry"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-7622-8494","authenticated-orcid":false,"given":"Ryuki","family":"Chatani","sequence":"first","affiliation":[{"name":"Department of Cardiology Kurashiki Central Hospital Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4794-7843","authenticated-orcid":false,"given":"Shunsuke","family":"Kubo","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kurashiki Central Hospital Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Nishiura","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kurashiki Central Hospital Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazunori","family":"Mushiake","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kurashiki Central Hospital Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sachiyo","family":"Ono","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kurashiki Central Hospital Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Maruo","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kurashiki Central Hospital Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazushige","family":"Kadota","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kurashiki Central Hospital Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuru","family":"Sago","sequence":"additional","affiliation":[{"name":"Department of Cardiology Toyohashi Heart Center  Aichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7551-3431","authenticated-orcid":false,"given":"Shuhei","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Cardiology Toyama University Hospital Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiko","family":"Asami","sequence":"additional","affiliation":[{"name":"Division of Cardiology Mitsui Memorial Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Hachinohe","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Sapporo Heart Center Sapporo Cardio Vascular Clinic Hokkaido Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toru","family":"Naganuma","sequence":"additional","affiliation":[{"name":"Department of Cardiology New Tokyo Hospital Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yohei","family":"Ohno","sequence":"additional","affiliation":[{"name":"Department of Cardiology Tokai University School of Medicine  Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoyuki","family":"Tani","sequence":"additional","affiliation":[{"name":"Department of Cardiology Sapporo East Tokushukai Hospital Hokkaido Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8122-3561","authenticated-orcid":false,"given":"Hideharu","family":"Okamatsu","sequence":"additional","affiliation":[{"name":"Department of Cardiology Saiseikai Kumamoto Hospital Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuki","family":"Mizutani","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine Kindai University Faculty of Medicine Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Cardiology Teikyo University School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaki","family":"Izumo","sequence":"additional","affiliation":[{"name":"Department of Cardiology St. Marianna University School of Medicine  Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mike","family":"Saji","sequence":"additional","affiliation":[{"name":"Department of Cardiology Sakakibara Heart Institute Tokyo Japan"},{"name":"Department of Cardiovascular Medicine Toho University Faculty of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shingo","family":"Mizuno","sequence":"additional","affiliation":[{"name":"Department of Cardiology Shonan Kamakura General Hospital Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9747-2511","authenticated-orcid":false,"given":"Hiroshi","family":"Ueno","sequence":"additional","affiliation":[{"name":"Department of Cardiology Toyama University Hospital Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinichi","family":"Shirai","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kokura Memorial 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