{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T16:10:34Z","timestamp":1780416634444,"version":"3.54.1"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T00:00:00Z","timestamp":1738195200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T00:00:00Z","timestamp":1738195200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Recent advancements in ultra\u2010high\u2010density mapping (UHDM) featuring automated functionalities have enhanced our understanding of micro\u2010reentrant atrial tachycardias (mAT) circuits and the precise localization of the origin.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the diagnostic support provided by an automated UHDM algorithm in guiding the ablation of mATs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Consecutive patients eligible for AT ablation in 22 Italian centers were prospectively enrolled. All ATs were comprehensively mapped in either the left or right atrium utilizing the RHYTHMIA mapping system. The LUMIPOINT tool was systematically employed to confirm electrogram fragmentation within this defined area.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 159 ATs analyzed, 97 (61.0%) were identified as macro\u2010reentrant ATs, 50 (31.4%) as focal ATs and 12 (7.5%) as mATs. Concerning the mAT group, the targeted activity was localized in the anterior wall in 4 cases (33.3%), in proximity to PVs in 3 cases (25%), along the left ridge in 2 cases (16.6%), and at the roof, in the free wall and along the CTI in 1 case (8.3%), respectively. Low voltage areas (&lt;\u20090.1\u2009mV) were detected in all mAT cases and colocalized with the origin site. Over a median of 288 [248\u2013349] days of follow\u2010up, 5 (3.1%) patients suffered from an AT\/AF arrhythmia recurrence: 3 (3.1%) were in the MAT group, 1 (2%) in the focal AT and 1 (8.3%) in the mAT group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A novel automated algorithm for mAT identification, coupled with ORION catheter, enables mAT description and transcatheter ablation of the localized origin of this rare form of AT results in a satisfactory procedural success rate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>Catheter Ablation of Arrhythmias With High\u2010Density Mapping System in the Real World Practice (CHARISMA).<\/jats:p>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\/\">http:\/\/clinicaltrials.gov\/<\/jats:ext-link>\n                      Identifier: NCT03793998.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.16563","type":"journal-article","created":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T04:48:51Z","timestamp":1738212531000},"page":"794-806","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Ultra High\u2010Density Mapping and Ablation of Localized Micro\u2010Reentrant Tachycardias: Insight From the CHARISMA Registry"],"prefix":"10.1111","volume":"36","author":[{"given":"Roberto","family":"Mantovan","sequence":"first","affiliation":[{"name":"Cardiology department \u201cS. Maria dei Battuti\u201d Hospital Via Brigata Bisagno Conegliano (TV) Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Bianchi","sequence":"additional","affiliation":[{"name":"Center of Excellence in Cardiovascular Sciences; Ospedale Isola Tiberina \u2013 Gemelli Isola Roma Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gemma","family":"Pelargonio","sequence":"additional","affiliation":[{"name":"Istituto di Cardiologia Universit\u00e0 Cattolica del Sacro Cuore Rome Italy"},{"name":"Department of Cardiovascular Sciences, Arrhythmology Unit Fondazione Policlinico Universitario Agostino Gemelli, IRCCS Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Solimene","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology Montevergine Clinic Mercogliano (AV) Italy"},{"name":"Department of Biomedical Sciences and Public Health Marche Polytechnic University Ancona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8823-0334","authenticated-orcid":false,"given":"Maurizio","family":"Malacrida","sequence":"additional","affiliation":[{"name":"Scientific Communication, CRMDx and Electrophysiology Divisions Boston Scientific Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Carbone","sequence":"additional","affiliation":[{"name":"Ospedale Santa Maria Dell'Addolorata Eboli (SA) Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Anselmino","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cardiovascular and Thoracic Department \u201cCitt\u00e0 della Salute e della Scienza\u201d Hospital Torino Italy"},{"name":"Department of Medical Sciences University of Torino Torino Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Gallucci","sequence":"additional","affiliation":[{"name":"Cardiology department \u201cS. Maria dei Battuti\u201d Hospital Via Brigata Bisagno Conegliano (TV) Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1421-9033","authenticated-orcid":false,"given":"Luca","family":"Segreti","sequence":"additional","affiliation":[{"name":"Second Division of Cardiology, Cardiac\u2010Thoracic\u2010Vascular Department, New Santa Chiara Hospital Azienda Ospedaliero Universitaria Pisana Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Galeazzi","sequence":"additional","affiliation":[{"name":"Electrophysiology and Electrostimulation Unit San Filippo Neri Hospital Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele","family":"Bianco","sequence":"additional","affiliation":[{"name":"Cardiology department IRCCS San Martino Polyclinic Hospital Genoa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Giomi","sequence":"additional","affiliation":[{"name":"The Cardiology and Electrophysiology Unit Santa Maria Nuova Hospital Firenze Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluca","family":"Mirizzi","sequence":"additional","affiliation":[{"name":"Interventional Electrophysiology Unit Fondazione Toscana Gabriele Monasterio Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Rossi","sequence":"additional","affiliation":[{"name":"Cardiology department Ospedale Guglielmo da Saliceto Piacenza Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluca","family":"Zingarini","sequence":"additional","affiliation":[{"name":"Cardiology department S. Maria della Misericordia Hospital Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raimondo","family":"Calvanese","sequence":"additional","affiliation":[{"name":"Cardiology department Ospedale del Mare \u2013 ASL Napoli 1 Centro Napoli Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Allocca","sequence":"additional","affiliation":[{"name":"Cardiology department \u201cS. Maria dei Battuti\u201d Hospital Via Brigata Bisagno Conegliano (TV) Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentino","family":"Ducceschi","sequence":"additional","affiliation":[{"name":"Cardiology department P.O. San Luca, Vallo Della Lucania (SA)  Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Dell'Era","sequence":"additional","affiliation":[{"name":"Electrophysiology Unit Azienda Ospedaliera Universitaria \u201cMaggiore della Carit\u00e0\u201d Novara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3938-4948","authenticated-orcid":false,"given":"Antonio","family":"Bisignani","sequence":"additional","affiliation":[{"name":"Center of Excellence in Cardiovascular Sciences; Ospedale Isola Tiberina \u2013 Gemelli Isola Roma Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6200-4088","authenticated-orcid":false,"given":"Roberto","family":"Scacciavillani","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Sciences, Arrhythmology Unit Fondazione Policlinico Universitario Agostino Gemelli, IRCCS Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Schillaci","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology Montevergine Clinic Mercogliano (AV) Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Rivetti","sequence":"additional","affiliation":[{"name":"Cardiology department \u201cS. 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