{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T02:08:11Z","timestamp":1790906891391,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T00:00:00Z","timestamp":1739145600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Identifying patients who will develop a need for right ventricular (RV) pacing after defibrillator (ICD) placement would help inform appropriate device selection, specifically to identify patients who might be more suitable for dual chamber or biventricular transvenous defibrillators versus single\u2010chamber or subcutaneous devices which do not provide pacing. We sought to determine predictors of RV pacing in patients who did not have a pacing indication at the time of initial ICD implant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This observational study assessed single\u2010chamber ICD recipients implanted from 2006 to 2016 from Boston Scientific's ALTITUDE database and linked to the NCDR\u00ae ICD Registry. The study population (<jats:italic>n<\/jats:italic>\u2009=\u200911\u2009044) of ICDs (programmed VVI mode at 40\u2009bpm), and without a clinical indication for pacing. was randomly divided into training and validation cohorts (70\/30) and characteristics associated with RV pacing were identified using logistic regression. The outcome was defined as the development of &gt;\u200920% RV pacing averaged over any continuous 90\u2010day period within 24 months after the ICD implant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients who developed &gt;\u200920% RV pacing (<jats:italic>n<\/jats:italic>\u2009=\u2009148, 1.3%) had a higher likelihood of being older, male, and with a history of syncope, ventricular tachycardia or cardiac arrest, hypertension, previous or ongoing AF, and longer PR, QRS duration and BUN level (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). After adjustment, PR\u2009&gt;\u2009230\u2009ms, history of AF, ongoing AF at time of implant, history of VT or cardiac arrest, and age &gt;\u200970 were independently associated with RV pacing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study provides insight into predictors of RV pacing in ICD recipients without pacing needs at baseline.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.16570","type":"journal-article","created":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T08:05:42Z","timestamp":1739261142000},"page":"807-812","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Predictors of Right Ventricular Pacing in Patients Undergoing Implantable Defibrillator Placement"],"prefix":"10.1111","volume":"36","author":[{"given":"James P.","family":"Hummel","sequence":"first","affiliation":[{"name":"Section of Cardiovascular Medicine Yale University School of Medicine New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhou","family":"Lan","sequence":"additional","affiliation":[{"name":"Section of Cardiovascular Medicine Yale University School of Medicine New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul W.","family":"Jones","sequence":"additional","affiliation":[{"name":"Boston Scientific St. Paul Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohan","family":"Khera","sequence":"additional","affiliation":[{"name":"Section of Cardiovascular Medicine Yale University School of Medicine New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth","family":"Stein","sequence":"additional","affiliation":[{"name":"Boston Scientific St. Paul Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeptha P.","family":"Curtis","sequence":"additional","affiliation":[{"name":"Section of Cardiovascular Medicine Yale University School of Medicine New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9348-3763","authenticated-orcid":false,"given":"Joseph G.","family":"Akar","sequence":"additional","affiliation":[{"name":"Section of Cardiovascular Medicine Yale University School of Medicine New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,10]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"275","article-title":"The Muscular Reactions of the Mammalian Ventricles to Artificial Surface Stimuli","volume":"37","author":"Wiggers C.","year":"1925","journal-title":"American Journal of Physiology"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.108.814608"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000072769.17295.B1"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.24.3115"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.608356"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.09.029"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.114.003030"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa013474"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa043399"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199711273372202"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.04.039"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.11.029"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.117.006937"},{"key":"e_1_2_8_15_1","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1093\/europace\/euu022","article-title":"A Prospective Randomized Trial of Single\u2010 or Dual\u2010Chamber Implantable Cardioverter\u2010Defibrillators to Minimize Inappropriate Shock Risk in Primary Sudden Cardiac Death Prevention","volume":"16","author":"Friedman P. 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