{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T21:29:47Z","timestamp":1782595787448,"version":"3.54.5"},"reference-count":12,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T00:00:00Z","timestamp":1742860800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Atrial tachycardias (AT) originating from the distal left atrial appendage (LAAd) are rare and pose significant challenges during catheter ablation. This report describes a case of incessant AT arising from the LAAd that was successfully treated using ethanol infusion therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A 70\u2010year\u2010old male patient with a history of incessant AT was referred to our center. Electrophysiological study and activation mapping were performed, revealing a focal AT originating from the LAAd with a cycle length of 544\u2009ms (110\u2009bpm).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Endocardial catheter ablation attempts within the left atrial appendage (LAA) failed to terminate the tachycardia. The LAA vein was difficult to visualize but was detected using a guidewire. Ethanol infusion into the LAA vein resulted in immediate termination of the LAAd AT. The patient remained in sinus rhythm during a 14\u2010month follow\u2010up period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Chemical ablation with ethanol infusion may serve as an effective alternative therapeutic strategy for managing focal ATs originating from the LAAd, although the success of this approach is contingent upon the anatomical accessibility and distribution of the LAA vein.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.16662","type":"journal-article","created":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T05:13:04Z","timestamp":1742965984000},"page":"1426-1431","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Ethanol Infusion Therapy for Incessant Atrial Tachycardia Arising From the Distal Left Atrial Appendage"],"prefix":"10.1111","volume":"36","author":[{"given":"Jia\u2010Yin","family":"Li","sequence":"first","affiliation":[{"name":"Department of Cardiology Affiliated Hospital of Jiaxing University, First Hospital of Jiaxing Jiaxing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin\u2010Feng","family":"Mo","sequence":"additional","affiliation":[{"name":"Department of Cardiology Affiliated Hospital of Jiaxing University, First Hospital of Jiaxing Jiaxing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,25]]},"reference":[{"issue":"2","key":"e_1_2_8_2_1","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1093\/europace\/eur302","article-title":"Focal Atrial Tachycardia Originating From the Distal Portion of the Left Atrial Appendage: Characteristics and Long\u2010Term Outcomes of Radiofrequency Ablation","volume":"14","author":"Yang Q.","year":"2012","journal-title":"Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euz212"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2007.06.008"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.19102\/icrm.2021.121004"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrcr.2020.11.024"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/CM9.0000000000001778"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jead343"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.16195"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2017.02.022"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.15966"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrcr.2019.03.006"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2019.02.009"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.16662","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T12:48:09Z","timestamp":1749732489000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.16662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,25]]},"references-count":12,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1111\/jce.16662"],"URL":"https:\/\/doi.org\/10.1111\/jce.16662","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,25]]},"assertion":[{"value":"2025-02-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}