{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T16:34:29Z","timestamp":1793637269289,"version":"4.5.1"},"reference-count":26,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T00:00:00Z","timestamp":1749686400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T00:00:00Z","timestamp":1749686400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>There are few comparative studies on the everyday clinical outcomes of commercially available pulsed field ablation (PFA) systems for atrial fibrillation (AF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study evaluates the acute efficacy and safety outcomes of the FARAPULSE\u2122 (pentaspline catheter) and PulseSelect\u2122 (circular catheter) system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>International, multicenter, registry on patients with paroxysmal or persistent AF, undergoing a first ablation using either PFA system between January 29th, 2024 and September 1st, 2024. Primary endpoints were electrical isolation of ablation targets, procedural characteristics and freedom from major adverse events within 30 days postprocedure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 402 patients were enrolled at the six participating centers, of whom 56.5% were treated with the pentaspline ablation\u2010catheter. Acute procedural efficacy was 100% for both groups. Use of the pentaspline ablation\u2010catheter was associated with significantly shorter procedural times (36.0\u2009min [IQR 31.0; 44.0]\n                      <jats:italic>vs.<\/jats:italic>\n                      49.0\u2009min [IQR 41.5;76.0]) compared to the circular ablation\u2010catheter (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Major adverse events were scarce and not different between cohorts. Two patients (0.5%) experienced a stroke and one patient (0.2%) had a serious vascular access site complication. One patient had a transient ischemic attack (0.2%). Minor vascular access site complications were more common in the pentaspline catheter group (11.9% vs. 1.1%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study showed excellent acute efficacy and safety for both PFA\u2010systems. Our findings reveal shorter procedural times with the pentaspline catheter, less minor access site complications with the circular catheter, and several procedural differences between the ablation systems, often driven by operator choice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.16761","type":"journal-article","created":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T01:45:12Z","timestamp":1749779112000},"page":"1957-1965","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Direct Comparison of Two Commercially Available Pulsed Field Ablation Systems for Atrial Fibrillation; Procedure Characteristics and Acute Outcomes"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0503-8791","authenticated-orcid":false,"given":"Bob G. S.","family":"Abeln","sequence":"first","affiliation":[{"name":"Department of Cardiology St. Antonius Hospital Nieuwegein the Netherlands"},{"name":"Department of Cardiology Amsterdam UMC Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6935-3985","authenticated-orcid":false,"given":"Marisa","family":"van der Graaf","sequence":"additional","affiliation":[{"name":"Department of Cardiology St. Antonius Hospital Nieuwegein the Netherlands"},{"name":"Department of Cardiology Amsterdam UMC Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2727-1508","authenticated-orcid":false,"given":"Dan L.","family":"Musat","sequence":"additional","affiliation":[{"name":"Snyder Center for Comprehensive Atrial Fibrillation, Valley Health System Paramus New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7561-7185","authenticated-orcid":false,"given":"Melanie A.","family":"Gunawardene","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Intensive Care medicine Asklepios St. Georg Clinic Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devi G.","family":"Nair","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology St. Bernards Medical Center Jonesboro Arkansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley P.","family":"Knight","sequence":"additional","affiliation":[{"name":"Division of Cardiology Northwestern University, Feinberg School of Medicine Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8254-2705","authenticated-orcid":false,"given":"Bradley","family":"Wilsmore","sequence":"additional","affiliation":[{"name":"Department of Cardiology John Hunter Hospital New Lambton New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max","family":"Liebregts","sequence":"additional","affiliation":[{"name":"Department of Cardiology St. Antonius Hospital Nieuwegein the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3832-1518","authenticated-orcid":false,"given":"Vincent F.","family":"van Dijk","sequence":"additional","affiliation":[{"name":"Department of Cardiology St. Antonius Hospital Nieuwegein the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurits C. 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F.","family":"Wijffels","sequence":"additional","affiliation":[{"name":"Department of Cardiology St. Antonius Hospital Nieuwegein the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7880-3730","authenticated-orcid":false,"given":"Jippe C.","family":"Balt","sequence":"additional","affiliation":[{"name":"Department of Cardiology St. Antonius Hospital Nieuwegein the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8003-7254","authenticated-orcid":false,"given":"Suneet","family":"Mittal","sequence":"additional","affiliation":[{"name":"Snyder Center for Comprehensive Atrial Fibrillation, Valley Health System Paramus New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Willems","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Intensive Care medicine Asklepios St. Georg Clinic Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4817-6614","authenticated-orcid":false,"given":"Nishant","family":"Verma","sequence":"additional","affiliation":[{"name":"Division of Cardiology Northwestern University, Feinberg School of Medicine Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graham","family":"Peigh","sequence":"additional","affiliation":[{"name":"Division of Cardiology Northwestern University, Feinberg School of Medicine Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael M.","family":"Malaty","sequence":"additional","affiliation":[{"name":"Department of Cardiology John Hunter Hospital New Lambton New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4591-4220","authenticated-orcid":false,"given":"Lucas V. 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