{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T12:03:02Z","timestamp":1784116982354,"version":"3.55.0"},"reference-count":11,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,7,9]],"date-time":"2025-07-09T00:00:00Z","timestamp":1752019200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Pentaspline ablation (31\u2009mm, Farapulse) catheter lesions can differ by pose, repetition, and contact, thus affecting morphology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>Lesion morphology may offer insights into suboptimal ablation durability and can help optimize ablation strategies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In 25 patients, 1\u20132 applications were delivered to pulmonary veins (PV, <jats:italic>n<\/jats:italic>\u2009=\u200916), posterior left atrium (LA, <jats:italic>n<\/jats:italic>\u2009=\u20096) and LA roof (<jats:italic>n<\/jats:italic>\u2009=\u20093). Pre, 1\u2010 and 5\u2010min postablation maps were created. Isolation area was identified by &lt;\u20090.15\u2009mV. Three patients after cavotricuspid isthmus (CTI) ablation were mapped.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Despite only 1 or 2 basket pose applications without rotation, all 16\/16 PVs (100%) were acutely isolated. Only 3\/16 PVs (12.5%) reconnected by 5\u2009min revealing asymmetric, band\u2010like perivenous lesions. Posterior LA flower applications were irregular, with the smallest mean dimensions of 14.9 and 17.7\u2009mm. Isolation area regressed acutely, more so for single but also for double applications. However, regression occurred only for PV (6.7\u2009\u00b1\u20096.0 vs. 1.3\u2009\u00b1\u20091.5\u2009cm<jats:sup>2<\/jats:sup>) and not for posterior wall lesions (2.9 [1.9\u20133.6] vs. 2 [1.65\u20132.4]\u2009cm<jats:sup>2<\/jats:sup>). Double roof applications resulted in circular, doughnut\u2010shaped, or even minimal lesions. Flower pose CTI lesions had median widths of 43.1, 21.3, and 24.9\u2009mm along the line.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Acute PV isolation always occurs despite minimal dose delivery and is unreliable for lesions assessment. Even double applications have relevant regression, and this occurs more so in PV than LA posterior wall. Despite 2 applications, posterior LA lesions were smaller than the catheter diameter and roof lesions footprints can vary widely. Dose related footprint assessments are needed to help optimize ablation and durability.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jce.16780","type":"journal-article","created":{"date-parts":[[2025,7,9]],"date-time":"2025-07-09T15:39:08Z","timestamp":1752075548000},"page":"2179-2187","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Endocardial Atrial Lesion Characteristics With Pentaspline Pulsed Field Ablation: Insights From Serial Mapping in Patients"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3464-3341","authenticated-orcid":false,"given":"Ariel","family":"Banai","sequence":"first","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srinivas","family":"Dukkipati","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0211-1690","authenticated-orcid":false,"given":"Keita","family":"Watanbe","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massaya","family":"Shinohara","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6826-8877","authenticated-orcid":false,"given":"Daniel","family":"Musikantow","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5638-4993","authenticated-orcid":false,"given":"Vivek Y.","family":"Reddy","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2221-8372","authenticated-orcid":false,"given":"Jacob","family":"Koruth","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,9]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2018.10.030"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.119.007781"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.120.009229"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.04.021"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2021.02.014"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.07.007"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2023.04.002"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2307291"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.124.013208"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.122.061497"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2023.12.015"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.16780","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T13:40:41Z","timestamp":1758202841000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.16780"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,9]]},"references-count":11,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1111\/jce.16780"],"URL":"https:\/\/doi.org\/10.1111\/jce.16780","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,9]]},"assertion":[{"value":"2025-05-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}