{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T15:07:55Z","timestamp":1777734475621,"version":"3.51.4"},"reference-count":23,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T00:00:00Z","timestamp":1755561600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T00:00:00Z","timestamp":1755561600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Uninterrupted left bundle branch pacing (LBBP) lead implantation with the endpoint of transition to selected (S)\u2010left bundle (LB) capture is feasible and safe during the procedure; however, the relatively long\u2010term outcomes remain unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The present study aimed to evaluate the short\u2010 to mid\u2010term performance and safety of uninterrupted LBBP lead implantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients who underwent successful LBBP and achieved the implantation endpoint, guided by continuous paced intracardiac electrogram monitoring, were enrolled. Electrocardiograms, pacing parameters, echocardiographic measurements, and complications associated with LBBP were assessed during follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 83 patients were enrolled in the study. The mean follow\u2010up duration was 14.2\u2009\u00b1\u20098.8 months. Pacing parameters, including R\u2010wave amplitude, pacing threshold, and impedance, remained stable throughout the follow\u2010up period for both unipolar and bipolar configurations. The transition from nonselected (NS)\u2010LB to S\u2010LB was observed at various unipolar pacing outputs during follow\u2010up, along with double transitions in bipolar pacing. The proportion of patients transitioning to NS\u2010LB, S\u2010LB, and left ventricular septum (LVS) under unipolar pacing at 8\u2009V, 3\u2009V, 2\u2009V, and 1\u2009V remained stable during follow\u2010up. Left ventricular ejection fraction (62.7\u2009\u00b1\u20097.0% vs 62.1\u2009\u00b1\u200911.9%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.723) remained stable during follow\u2010up compared to baseline. Left ventricular end\u2010diastolic dimension (47.5\u2009\u00b1\u20095.6\u2009mm vs. 51.1\u2009\u00b1\u20097.1\u2009mm,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001) decreased significantly.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Uninterrupted LBBP lead implantation with the endpoint of transition to S\u2010LB, was safe and feasible in short\u2010 to mid\u2010term observations. It can improve LVEF in patients with HFrEF.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.70054","type":"journal-article","created":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T05:04:59Z","timestamp":1755666299000},"page":"2839-2848","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Short\u2010 to Mid\u2010Term Efficacy and Safety of Left Bundle Branch Pacing Guided by Continuous Uninterrupted Paced Intracardiac Electrogram Monitoring Targeting Transition to Selective Left Bundle Branch Capture"],"prefix":"10.1111","volume":"36","author":[{"given":"Hao","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine Ningbo No. 2 Hospital Ningbo Zhejiang 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