{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T02:35:13Z","timestamp":1778812513095,"version":"3.51.4"},"reference-count":12,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:00:00Z","timestamp":1759968000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:00:00Z","timestamp":1759968000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>\n                      Patients with surgically repaired\n                      <jats:sc>D<\/jats:sc>\n                      \u2010transposition of the great arteries (\n                      <jats:sc>D<\/jats:sc>\n                      \u2010TGA) via atrial switch are at high risk of cavotricuspid isthmus (CTI) dependent atrial flutter, which can be challenging to address. High rates of CTI\u2010dependent flutter recurrence after initial ablation have been reported, but clinical predictors of recurrence remain poorly understood.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We identified patients with a history of\n                      <jats:sc>d<\/jats:sc>\n                      \u2010TGA repaired with atrial switch undergoing catheter ablation for CTI\u2010 dependent flutter from 2011 to 2023. Demographics, cardiac imaging, and procedural characteristics were analyzed. Clinical and procedural characteristics were compared between patients with and without recurrence.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 19 patients who underwent catheter ablation, 9 (47.3%) had recurrent CTI\u2010dependent flutter over a median follow\u2010up of 2.96 (IQR 0.88\u20135.08) years. Median recurrence time was 1.3 years (IQR 0.33\u20132.0) years postablation. Moderate or greater dilation of the systemic ventricle (100% vs. 54%\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01) and systemic atrioventricular valve (AV) regurgitation (60% vs. 8%\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01) correlated with recurrence. No differences were noted in need for pulmonary venous access, flutter cycle length, split duration, or transisthmus time.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Nearly half of patients with repaired\n                      <jats:sc>d<\/jats:sc>\n                      \u2010TGA undergoing index CTI\u2010dependent flutter ablation experience recurrence. Clinical and anatomic factors such as systolic dilation and AV regurgitation in the systemic ventricle were significantly associated with recurrence and provide operators with information on at\u2010risk profiles which may influence postprocedural care and monitoring.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.70119","type":"journal-article","created":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T04:30:45Z","timestamp":1760070645000},"page":"3042-3050","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Clinical Predictors of Recurrent Cavotricuspid Isthmus Flutter After Catheter Ablation in Patients With Dextro\u2010Transposition of the Great Arteries"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7146-8896","authenticated-orcid":false,"given":"Alex","family":"Grubb","sequence":"first","affiliation":[{"name":"Department of Medicine Division of Cardiology, Section of Electrophysiology, University of Colorado Anschutz Medical Center Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4761-8460","authenticated-orcid":false,"given":"Radoslaw","family":"Nabrzyski","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Internal Medicine, University of Colorado Anschutz Medical Center Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikhil","family":"Shamapant","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Internal Medicine, University of Colorado Anschutz Medical Center Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francis","family":"Zirille","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Internal Medicine, University of Colorado Anschutz Medical Center Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kishan","family":"Padalia","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Cardiology, Section of Electrophysiology, University of Colorado Anschutz Medical Center Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lukasz","family":"Cerbin","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Cardiology, Section of Electrophysiology, University of Colorado Anschutz Medical Center Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Holzemer","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Cardiology, Section of Electrophysiology, University of Colorado Anschutz Medical Center Aurora Colorado USA"},{"name":"Department of Pediatrics Children's Hospital Colorado Auora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael A.","family":"Rosenberg","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Cardiology, Section of Electrophysiology, University of Colorado Anschutz Medical Center Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lohit","family":"Garg","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Cardiology, Section of Electrophysiology, University of Colorado Anschutz Medical Center Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8073-5773","authenticated-orcid":false,"given":"Christopher","family":"Barrett","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Cardiology, Section of Electrophysiology, University of Colorado Anschutz Medical Center Aurora Colorado USA"},{"name":"Denver Health Medical Center, Heart and Vascular Program Denver Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6797-1803","authenticated-orcid":false,"given":"Syed Rafay Ali","family":"Sabzwari","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Cardiology, Section of Electrophysiology, University of Colorado Anschutz Medical Center Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexis Z.","family":"Tumolo","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Cardiology, Section of Electrophysiology, University of Colorado Anschutz Medical Center Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul D.","family":"Varosy","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Cardiology, Section of Electrophysiology, University of Colorado Anschutz Medical Center Aurora Colorado USA"},{"name":"Department of Medicine Rocky Mountain Regional VA Medical Center, Division of Cardiology, Section of Electrophysiology Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew M.","family":"Zipse","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Cardiology, Section of Electrophysiology, University of Colorado Anschutz Medical Center Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1811-5730","authenticated-orcid":false,"given":"Carmel","family":"Ashur","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Cardiology, Section of Electrophysiology, University of Colorado Anschutz Medical Center Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Adewumi","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Cardiology, Section of Electrophysiology, 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Section of Electrophysiology, University of Colorado Anschutz Medical Center Aurora Colorado USA"},{"name":"Department of Pediatrics Children's Hospital Colorado Auora Colorado USA"},{"name":"Department of Medicine Rocky Mountain Regional VA Medical Center, Division of Cardiology, Section of Electrophysiology Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,9]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200002033420507"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(95)70392-6"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccep.2014.05.014"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euac053.547"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2022.06.020"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2008.11.022"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eus402"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.121.010546"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2016.11.031"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvq357"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00031.2009"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.19102\/icrm.2021.120805"}],"container-title":["Journal 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