{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T16:45:29Z","timestamp":1790181929646,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","license":[{"start":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:00:00Z","timestamp":1761004800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Atrial fibrillation (AF) is the most common sustained arrhythmia and raises ischemic stroke risk fivefold, even when asymptomatic. Early detection and timely initiation of oral anticoagulation can significantly reduce stroke incidence, motivating interest in population\u2010level AF screening. This review synthesizes findings from large\u2010scale trials and digital health studies, including wearable device\u2014based detection, and highlights both benefits and limitations of screening. Benefits include earlier diagnosis of silent AF, timely treatment, and potential reductions in stroke burden. However, drawbacks such as false positives, inconclusive results, unnecessary follow\u2010up testing, patient anxiety, and resource strain remain important concerns. Emerging strategies\u2014such as AI\u2010guided risk stratification, improved signal processing, and integrated digital care pathways\u2014offer promise in improving diagnostic accuracy, reducing false alarms, and streamlining clinical management. When implemented through targeted, technology\u2010enhanced approaches, AF screening has the potential to benefit patients and healthcare systems by preventing strokes and optimizing resource use. However, its overall value depends on balancing improved detection and clinical outcomes against the risks of overdiagnosis, psychological burden, and system costs. Ultimately, the success of AF screening will require careful integration of novel technologies with evidence\u2010based care pathways to ensure clinically meaningful and sustainable healthcare impact.<\/jats:p>","DOI":"10.1111\/jce.70153","type":"journal-article","created":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T09:05:56Z","timestamp":1761037556000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Atrial Fibrillation Screening: Burden or Benefit for Patients and the Healthcare System"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8597-7165","authenticated-orcid":false,"given":"Keitaro","family":"Senoo","sequence":"first","affiliation":[{"name":"Department of Cardiac Arrhythmia Research and Innovation, Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan"},{"name":"Department of Cardiovascular Medicine, Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,21]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.lanepe.2023.100786","article-title":"Atrial Fibrillation: Epidemiology, Screening and Digital Health","volume":"37","author":"Linz D.","year":"2024","journal-title":"Lancet Regional Health \u2010 Europe"},{"issue":"9989","key":"e_1_2_11_3_1","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/S0140-6736(14)61774-8","article-title":"50 Year Trends in Atrial Fibrillation Prevalence, Incidence, Risk Factors, and Mortality in the Framingham Heart Study: A Cohort Study","volume":"386","author":"Schnabel R. 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