{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T16:15:14Z","timestamp":1772986514675,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T00:00:00Z","timestamp":1761523200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T00:00:00Z","timestamp":1761523200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Premature ventricular contractions (PVCs) originating from the proximal left anterior fascicle (LAF) are rarely discussed. We aimed to describe the characteristics and ablation outcome of PVCs originating from the proximal LAF and propose a stepwise approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method and Results<\/jats:title>\n                    <jats:p>From 2018 to 2024, 16 patients (nine males) with proximal LAF\u2013PVCs who underwent ablation were enrolled, and their electrophysiological characteristics and procedural details were analyzed. The acute procedural outcomes were complete success, success with residual nonclinical PVCs, and partial success (decrease in clinical PVCs). The electrocardiographs of the PVCs showed a right bundle branch block with an inferior axis. In the initial ablation attempt, targeting the earliest left ventricular (LV) endocardial activation site eliminated clinical PVC in 14 patients. Nonclinical PVC occurred in seven patients. A second attempt from the right coronary cusp (RCC) was made in four patients (three nonclinical and one clinical PVC), which resulted in complete success. One patient (6.3%, partial success) had PVC recurrence. Sites with a successful ablation showed a significantly greater Fascicle\u2010QRS[PVC] interval, Delta Fascicle\u2010QRS[PVC\u2013Sinus] interval, and more reverse fascicle potentials than other sites. Patients who underwent successful supra\u2010RCC ablation had a shorter RCC\u2010LV earliest activation site distance (EAS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This is the first study to investigate the dynamic electrogram property in LAF\u2013PVC ablation. The Fascicle\u2013PVC interval and reverse fascicle are useful for predicting acute ablation success. The RCC approach may be effective in cases with a short RCC\u2013LV EAS distance. Nonclinical PVC morphology could be due to LAF block and might not affect the long\u2010term outcome after careful mapping.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.70164","type":"journal-article","created":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:22:27Z","timestamp":1761628947000},"page":"7-16","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Premature Ventricular Contractions From the Proximal Left Anterior Fascicle: Insight From the Electrophysiologic and Anatomic Parameters"],"prefix":"10.1111","volume":"37","author":[{"given":"Xuan Hoang","family":"Le","sequence":"first","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Interventional Cardiology Center, Tam Anh General Hospital Ho Chi Minh Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3282-7523","authenticated-orcid":false,"given":"Chin Yu","family":"Lin","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Medicine National Yang\u2010Ming Chiao\u2010Tung University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7461-2793","authenticated-orcid":false,"given":"Fa Po","family":"Chung","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Medicine National Yang\u2010Ming Chiao\u2010Tung University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8395-1052","authenticated-orcid":false,"given":"Yenn Jiang","family":"Lin","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Medicine National Yang\u2010Ming Chiao\u2010Tung University Taipei Taiwan"},{"name":"Heart Rhythm Center, Division of Cardiology, Department of Medicine Taichung Veterans General Hospital  Taichung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0545-2156","authenticated-orcid":false,"given":"Shih Lin","family":"Chang","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Medicine National Yang\u2010Ming Chiao\u2010Tung University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9102-227X","authenticated-orcid":false,"given":"Li Wei","family":"Lo","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Medicine National Yang\u2010Ming Chiao\u2010Tung University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5715-2070","authenticated-orcid":false,"given":"Yu Feng","family":"Hu","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Medicine National Yang\u2010Ming Chiao\u2010Tung University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ta Chuan","family":"Tuan","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Medicine National Yang\u2010Ming Chiao\u2010Tung University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6587-3094","authenticated-orcid":false,"given":"Tze Fan","family":"Chao","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Medicine National Yang\u2010Ming Chiao\u2010Tung University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo Nan","family":"Liao","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Medicine National Yang\u2010Ming Chiao\u2010Tung University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guan Yi","family":"Li","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Medicine National Yang\u2010Ming Chiao\u2010Tung University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2612-0057","authenticated-orcid":false,"given":"Ting Yung","family":"Chang","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Medicine National Yang\u2010Ming Chiao\u2010Tung University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Kuo","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Medicine National Yang\u2010Ming Chiao\u2010Tung University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng I.","family":"Wu","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Medicine National Yang\u2010Ming Chiao\u2010Tung University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chih Min","family":"Liu","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Medicine National Yang\u2010Ming Chiao\u2010Tung University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shin Huei","family":"Liu","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Medicine National Yang\u2010Ming Chiao\u2010Tung University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming Jen","family":"Kuo","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Heart Rhythm Center, Division of Cardiology, Department of Medicine Taichung Veterans General Hospital  Taichung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu\u2010Shan","family":"Huang","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Heart Rhythm Center, Division of Cardiology, Department of Medicine Taichung Veterans General Hospital  Taichung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lo Chieh","family":"Ling","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Medicine National Yang\u2010Ming Chiao\u2010Tung University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng Han","family":"Chan","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Medicine National Yang\u2010Ming Chiao\u2010Tung University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Da Wei","family":"Chang","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Division of Cardiology, Department of Medicine Tri\u2010Service General Hospital Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4732-7855","authenticated-orcid":false,"given":"Minh Nhut","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula Victoria Catherine Cheng","family":"Bromeo","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6026-353X","authenticated-orcid":false,"given":"Shih Ann","family":"Chen","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center and Cardiovascular Center, Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Medicine National Yang\u2010Ming Chiao\u2010Tung University Taipei Taiwan"},{"name":"Heart Rhythm Center, Division of Cardiology, Department of Medicine Taichung Veterans General Hospital  Taichung Taiwan"},{"name":"National Chung Hsing University  Taichung Taiwan"},{"name":"Department of Medicine China Medical University College of Medicine  Taichung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,27]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-022-01428-1"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.16549"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2014.05.010"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.53.4.609"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/circep.119.008173"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.07.095"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.116.002476"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.16714"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcha.2025.101664"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euw143"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrcr.2025.01.005"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2022.05.010"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2022.05.029"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcdd9090293"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2014.06.024"}],"container-title":["Journal 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