{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T22:21:30Z","timestamp":1790720490514,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T00:00:00Z","timestamp":1764115200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T00:00:00Z","timestamp":1764115200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Conventional substrate mapping for scar\u2010related ventricular tachycardia (VT) often fails to fully delineate critical arrhythmogenic components. Functional mapping strategies using extrastimuli have shown promise but are limited by procedural complexity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In total, 57 patients undergoing VT ablation between March 2023 and October 2024 were included in the study. Patients were grouped based on whether targeted double extrastimuli mapping (focused DEMAP) was used to guide mapping and ablation. Mapping was performed using EnSite X with omnipolar technology. Clinical and procedural outcomes were compared between focused DEMAP and non\u2010DEMAP groups with outcomes follow\u2010up at 12 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Focused DEMAP revealed a significantly higher correlation between DZs and VT critical isthmuses compared to sinus rhythm mapping (75.9% vs. 37.1%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01). VT\u2010free survival at 12 months was higher in the DEMAP group (88.03%) than in the non\u2010DEMAP group (58.10%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04). Trends also favored DEMAP in reducing cardiovascular hospitalization (10.55% vs. 24.70%) and mortality, though not statistically significant. Overall procedure time was similar mainly driven by less time during ablation and a lower mean ablated area in the focused DEMAP group compared to the non\u2010DEMAP group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The focused DEMAP, a focused double extrastimulus mapping strategy, enhances VT substrate identification and is associated with improved VT\u2010free survival without prolonging procedure time. This approach may refine substrate\u2010based ablation and optimize lesion targeting without increasing procedural burden.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.70196","type":"journal-article","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T06:25:26Z","timestamp":1764224726000},"page":"137-148","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Outcomes of Focused Double Extrastimuli Mapping and Ablation in Ventricular Tachycardia"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0200-848X","authenticated-orcid":false,"given":"Surachat","family":"Jaroonpipatkul","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Medicine University of Utah Health Salt Lake City Utah USA"},{"name":"Nora Eccles Harrison Cardiovascular Research Training Institute University of Utah Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea N.","family":"Keithler","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine University of Utah Health Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thipsukhon","family":"Sathapanasiri","sequence":"additional","affiliation":[{"name":"Department of Pharmacotherapy, College of Pharmacy University of Utah Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harikrishna","family":"Tandri","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Vanderbilt University Medical Center Nashville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Jared Bunch","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine University of Utah Health Salt Lake City Utah 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