{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T15:01:22Z","timestamp":1780498882899,"version":"3.54.1"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T00:00:00Z","timestamp":1769558400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T00:00:00Z","timestamp":1769558400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Focal cryoablation (CRYO) is an alternative to radiofrequency ablation (RFA) in patients with atrioventricular nodal reentrant tachycardia (AVNRT) with low risk of atrioventricular (AV) block and high arrhythmia recurrence. There are limited studies showing that longer duration and bonus CRYO decreases arrhythmia recurrence compared to standard CRYO (two times 240\u2009s). In our study, it was planned to investigate the efficacy of a single 480\u2010s CRYO protocol on the long\u2010term risk of AVNRT recurrence and persistent AV block in AVNRT patients compared to standard CRYO and RFA protocols.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Two hundred sixty patients who underwent ablation for AVNRT were enrolled in this retrospective cohort study. Patients were divided into three groups: standard CRYO group (Group I), single 480\u2010s CRYO group (Group II), and RFA group (Group III). Groups I, II, and III included 92, 68, and 100 AVNRT patients, respectively. Patients were followed for 32\u2009\u00b1\u20099.1 months after ablation. The groups were compared for acute process success, transient AV block, persistent AV block, and long\u2010term arrhythmic recurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In the follow\u2010up, AVNRT recurrence was determined in 10, 2, and 3 patients in Groups I, II, and III, respectively (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The frequency of AVNRT recurrence was significantly higher in Group I than in Groups II and III (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). It was found that the frequency of AVNRT recurrence was similar between Groups II and III. In Groups I and II, permanent AV block associated with ablation was not observed in either case. However, in Group III, only two patients were found to have permanent AV block. There were no statistical differences between groups in terms of permanent AV block development. Acute process success and transient AV block development were similar among groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>In our study, it was shown that AVNRT patients can be treated effectively and safely with a single 480\u2010s CRYO protocol among catheter ablation methods. While this new CRYO protocol significantly reduces the long\u2010term arrhythmic recurrence rate compared to standard CRYO, it is similarly effective with RFA.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.70209","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T05:32:59Z","timestamp":1769664779000},"page":"714-723","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Single 480\u2010s Cryoablation Reduces Long\u2010Term Arrhythmia Recurrence Rate Than Standard Cryoablation in Patients With AVNRT"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6232-4567","authenticated-orcid":false,"given":"Hasan","family":"Koca","sequence":"first","affiliation":[{"name":"Department of Cardiology University of Health Sciences \u2013 Adana Health Practice and Research Center Adana Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6694-814X","authenticated-orcid":false,"given":"Hazar","family":"Harbal\u0131o\u011flu","sequence":"additional","affiliation":[{"name":"Department of Cardiology University of Health Sciences \u2013 Adana Health Practice and Research Center Adana Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6352-4651","authenticated-orcid":false,"given":"Mustafa L\u00fctfullah","family":"Ard\u0131c","sequence":"additional","affiliation":[{"name":"Department of Cardiology University of Health Sciences \u2013 Adana Health Practice and Research Center Adana Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0070-5281","authenticated-orcid":false,"given":"Yahya Kemal","family":"Icen","sequence":"additional","affiliation":[{"name":"Department of Cardiology University of Health Sciences \u2013 Adana Health Practice and Research Center Adana Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0444-674X","authenticated-orcid":false,"given":"Fadime","family":"Koca","sequence":"additional","affiliation":[{"name":"Department of Cardiology Cukurova State Hospital Adana Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4450-2183","authenticated-orcid":false,"given":"Halil","family":"Co\u015fkun","sequence":"additional","affiliation":[{"name":"Department of Cardiology University of Health Sciences \u2013 Adana Health Practice and Research Center Adana Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5232-8466","authenticated-orcid":false,"given":"Abdullah Eren","family":"\u00c7etin","sequence":"additional","affiliation":[{"name":"Department of Cardiology University of Health Sciences \u2013 Adana Health Practice and Research Center Adana Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3519-0962","authenticated-orcid":false,"given":"Durmu\u015f Y\u0131ld\u0131ray","family":"\u015eahin","sequence":"additional","affiliation":[{"name":"Department of Cardiology University of Health Sciences \u2013 Adana Health Practice and Research Center Adana Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3000-4200","authenticated-orcid":false,"given":"Mevlut","family":"Koc","sequence":"additional","affiliation":[{"name":"Department of Cardiology University of Health Sciences \u2013 Adana Health Practice and Research Center Adana Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,28]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz467"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-013-9842-2"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12247"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2012.03514.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.14915"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-006-9028-2"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rec.2014.11.011"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2005.10.005"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(92)90994-a"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2007.10.013"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eun094"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euy225"},{"key":"e_1_2_10_13_2","doi-asserted-by":"crossref","unstructured":"Erratum in: Europace 2019 Apr 1;21(4):669 doi:10.1093\/europace\/euy302.","DOI":"10.1093\/europace\/euy302"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-019-00585-0"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/joa3.70072"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.970350"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2009.11.029"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-012-9732-z"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2008.01224.x"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.112.973651"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13367"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.6515\/ACS.201903_35(2).20180903A"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2023.04.006"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.36660\/abc.20230604"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.15849"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0033-0620(99)70024-1"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.70209","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jce.70209","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.70209","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T14:03:01Z","timestamp":1780495381000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.70209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,28]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1111\/jce.70209"],"URL":"https:\/\/doi.org\/10.1111\/jce.70209","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,28]]},"assertion":[{"value":"2025-07-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}