{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T13:34:34Z","timestamp":1786714474404,"version":"build-2736575974"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T00:00:00Z","timestamp":1766534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T00:00:00Z","timestamp":1766534400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Activation mapping of scar\u2010mediated ventricular tachycardias (VT) are often limited by hemodynamic instability. Substrate mapping and 12\u2010lead ECG localization of VT exit site is often limited by variable scar complexity. Emphasis on other mapping strategies in sinus rhythm would improve catheter ablation success in such cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The aim was to investigate the level of agreement between artificial intelligence (AI) based 12\u2010lead ECG localization of VT exit site and mapping utilizing pace\u2010mapping and mapping of channels of slow conduction within the scar tissue of hemodynamically unstable VT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a single\u2010center proof\u2010of\u2010concept study that included patients who underwent catheter ablation procedure of hemodynamically unstable scar\u2010mediated VT. The performance of AI\u2010assisted ECG analysis of VT exit site (Vektor Medical, San Diego, CA) was compared with sites of successful ablation based on substrate mapping in sinus rhythm.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of nine hemodynamically unstable VT rhythms were induced in four patients. In the seven VTs were AI\u2010assisted ECG analysis was used; there was a 100% level of agreement with the site of successful ablation based on substrate mapping. Ablation targeting those sites resulted in non\u2010induction of all induced and mapped VTs. None of the four patients had device therapy for recurrent VT or all\u2010cause mortality at 6 months of follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A multi\u2010strategic approach utilizing digitalized analysis of 12\u2010lead ECG of VT exit site, pace\u2010mapping and mapping of channels of slow conduction in scar tissue, has the potential to enhance successful catheter ablation of hemodynamically unstable VT.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.70230","type":"journal-article","created":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T08:33:05Z","timestamp":1766565185000},"page":"381-389","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Novel Workflow Combining Artificial Intelligence\u2014Twelve Lead Electrocardiographic Analysis and Real\u2010Time Mapping for Hemodynamically Unstable Ventricular Tachycardia"],"prefix":"10.1111","volume":"37","author":[{"given":"Faris","family":"Haddadin","sequence":"first","affiliation":[{"name":"University of Minnesota Twin Cities Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven A.","family":"Kessler","sequence":"additional","affiliation":[{"name":"University of Minnesota Twin Cities Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Prisco","sequence":"additional","affiliation":[{"name":"University of Minnesota Twin Cities Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Zhi","sequence":"additional","affiliation":[{"name":"University of Minnesota Twin Cities Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madeeha","family":"Rizvi","sequence":"additional","affiliation":[{"name":"Des Moines University Des Moines Iowa 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