{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T15:01:17Z","timestamp":1780498877057,"version":"3.54.1"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T00:00:00Z","timestamp":1769558400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T00:00:00Z","timestamp":1769558400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Catheter ablation is increasingly used in patients with ventricular tachycardia (VT) and an implantable cardioverter\u2010defibrillator (ICD) device in situ, but its real\u2010world safety and effectiveness remain underexplored in this high\u2010risk population. We aim to evaluate in\u2010hospital outcomes associated with catheter ablation in VT patients with a history of ICD implantation using a large, nationally representative dataset.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a retrospective cohort study using the National Inpatient Sample (2016\u20132021) to identify adult hospitalizations with VT and prior ICD device insertion. Patients were stratified into ablation and non\u2010ablation groups. Propensity score matching was used to balance baseline characteristics. Primary outcome was in\u2010hospital mortality; secondary outcomes included acute heart failure, ST\u2010elevation myocardial infarction (STEMI), sepsis, major adverse cardiac events (MACE), and procedure\u2010related complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 395,290 hospitalizations with VT and prior ICD, 4.9% underwent ablation. Catheter ablation remained independently associated with reduced in\u2010hospital mortality (adjusted odds ratio [aOR]\u2009=\u20090.59; 95% CI: 0.48\u20130.74), acute heart failure (aOR\u2009=\u20090.59; 95% CI: 0.54\u20130.64), ST\u2010elevation MI (aOR\u2009=\u20090.44; 95% CI: 0.36\u20130.54), and sepsis (aOR\u2009=\u20090.34; 95% CI: 0.26\u20130.45) (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The composite MACE outcome also showed a reduced odds ratio for ablation (aOR\u2009=\u20090.76; 95% CI: 0.68\u20130.85;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). However, ablation was also associated with higher odds of cardiac tamponade (aOR\u2009=\u20098.33; 95% CI: 5.92\u201311.73), cardiogenic shock (aOR\u2009=\u20091.36; 95% CI: 1.19\u20131.55), need for mechanical circulatory support (aOR\u2009=\u20095.36; 95% CI: 4.63\u20136.21), and prolonged hospital stay \u2265\u20097 days (aOR\u2009=\u20091.69; 95% CI: 1.57\u20131.82) (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In patients with VT and prior ICD implantation, catheter ablation is associated with improved in\u2010hospital outcomes but higher procedural risks. These findings support its selective use in experienced centers capable of managing complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.70273","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T05:20:13Z","timestamp":1769664013000},"page":"733-739","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Ventricular Tachycardia Ablation Outcomes in Patients With Previous Implantable Cardioverter\u2010Defibrillator Insertion: A Multicenter Cohort Study"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4298-5456","authenticated-orcid":false,"given":"Ali Saad","family":"Al\u2010Shammari","sequence":"first","affiliation":[{"name":"College of Medicine University of Baghdad Baghdad Iraq"},{"name":"West Virginia University Camden Clark Medical Center Parkersburg West Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7155-2094","authenticated-orcid":false,"given":"Ankur","family":"Singla","sequence":"additional","affiliation":[{"name":"Northwest Health\u2010Porter Valparaiso Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1744-4217","authenticated-orcid":false,"given":"Adishwar","family":"Rao","sequence":"additional","affiliation":[{"name":"Robert Packer Hospital\/Guthrie Clinic Sayre Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7740-1453","authenticated-orcid":false,"given":"Ahmed Sermed","family":"Al Sakini","sequence":"additional","affiliation":[{"name":"College of Medicine University of Baghdad Baghdad Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5122-8200","authenticated-orcid":false,"given":"Ameer","family":"Awashra","sequence":"additional","affiliation":[{"name":"Department of Medicine An\u2010Najah National University Nablus Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Misha","family":"Khan","sequence":"additional","affiliation":[{"name":"Liaquat National Hospital and Medical College Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Tareq","family":"Mutar","sequence":"additional","affiliation":[{"name":"College of Medicine University of Baghdad Baghdad Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khadeeja Ali","family":"Hamzah","sequence":"additional","affiliation":[{"name":"Al\u2010Kindy College of Medicine University of Baghdad Baghdad Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5174-1034","authenticated-orcid":false,"given":"Ahmed","family":"Al\u2010Kaisey","sequence":"additional","affiliation":[{"name":"Royal Melbourne Hospital Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haider","family":"Al\u2010Taii","sequence":"additional","affiliation":[{"name":"University of Texas Medical Branch Galveston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2814-7314","authenticated-orcid":false,"given":"Raheel","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Newcastle University Newcastle upon Tyne UK"},{"name":"National Heart and Lung Institute Imperial College London  UK"},{"name":"Freeman Hospital Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saif","family":"Syed","sequence":"additional","affiliation":[{"name":"Royal College of Surgeons in Ireland Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keerat Rai","family":"Ahuja","sequence":"additional","affiliation":[{"name":"Northwest Health\u2010Porter Valparaiso Indiana 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