{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T15:01:30Z","timestamp":1780498890629,"version":"3.54.1"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T00:00:00Z","timestamp":1772928000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T00:00:00Z","timestamp":1772928000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Left bundle branch area pacing (LBBAP) is a novel physiological pacing technique, but its relatively complex procedure limits its widespread clinical application. To compare the clinical efficacy of probe\u2010LBBAP (p\u2010LBBAP, a method involving pre\u2010positioning a ventricular lead guidewire to the optimal physiological pacing site in the interventricular septum before guiding ventricular lead implantation) and conventional LBBAP (c\u2010LBBAP) in patients undergoing physiological cardiac pacing. A retrospective analysis was conducted on 20 patients who received physiological pacing. Based on the LBBAP lead implantation technique, patients were divided into the p\u2010LBBAP group (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200910) and the c\u2010LBBAP group (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200910). Baseline clinical data, including medical history, QRS duration, and echocardiographic parameters, were collected. Procedural reports were reviewed to compare intraoperative LBBAP lead implantation time, fluoroscopy time, stimulus to left ventricular activation time (Sti\u2010LVAT), postoperative paced QRS duration, pacemaker parameters, and echocardiographic outcomes. A total of 20 patients were included, with a mean age of (69.50\u2009\u00b1\u200910.76) years, including 11 males (55%, 11\/20). The cohort was divided into the c\u2010LBBAP group (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200910) and the p\u2010LBBAP group (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200910). Compared with the c\u2010LBBAP group, the p\u2010LBBAP group showed significantly reduced LBBAP lead implantation time ([288.70\u2009\u00b1\u200959.99]\u2009s vs. [370.6\u2009\u00b1\u200959.11]\u2009s,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.007) and fluoroscopy time ([330.80\u2009\u00b1\u200952.67]\u2009s vs. [383.2\u2009\u00b1\u200949.04]\u2009s,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.034). Regarding pacemaker parameters, no statistically significant differences were observed between the p\u2010LBBAP and c\u2010LBBAP groups in postoperative ventricular lead threshold (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.721) or impedance (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.725). Similarly, no significant differences were found in Postoperative paced QRS duration (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.783) and paced QRS narrowing rate (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.869). At the 6\u2010month follow\u2010up, LBBAP lead thresholds and impedance remained stable in both groups. Echocardiographic follow\u2010up revealed no significant difference in the improvement of left ventricular ejection fraction (LVEF) (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.692). No procedure\u2010related complications occurred in either group. In physiological pacing procedures, the p\u2010LBBAP technique significantly reduces LBBAP lead implantation time and fluoroscopy time while maintaining stable lead thresholds and impedance during follow\u2010up, demonstrating its reliability as a physiological pacing approach.\n                  <\/jats:p>","DOI":"10.1111\/jce.70282","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T04:24:18Z","timestamp":1773030258000},"page":"837-846","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy Comparison Between Conventional and Probe Methods for Left Bundle Branch Area Pacing"],"prefix":"10.1111","volume":"37","author":[{"given":"Songqing","family":"Yang","sequence":"first","affiliation":[{"name":"The First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoruo","family":"Zhang","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geer","family":"Sheng","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuran","family":"Chen","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodi","family":"Yu","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunlin","family":"Gong","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoran","family":"Jing","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanfeng","family":"Tian","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaoyue","family":"Zhong","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8637-8714","authenticated-orcid":false,"given":"Siting","family":"Hong","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-6596-7960","authenticated-orcid":false,"given":"Zhaojun","family":"Wang","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,8]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.06.006"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.101.8.869"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euy058"},{"issue":"12","key":"e_1_2_9_5_1","first-page":"1736.e1","article-title":"A Novel Pacing Strategy With Low and Stable Output: Pacing the Left Bundle Branch Immediately Beyond the Conduction Block","volume":"33","author":"Weijian H.","year":"2017","journal-title":"Canadian Journal of Cardiology"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2019.05.011"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2019.06.016"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.15123"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2021.08.033"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2019.05.014"},{"issue":"2","key":"e_1_2_9_11_1","first-page":"329","article-title":"Simplifying Physiological Left Bundle Branch Area Pacing Using a New Nine\u2010Partition Method","volume":"37","author":"Junmeng Z.","year":"2021","journal-title":"Canadian Journal of Cardiology"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2020.05.018"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.14140"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2022.01.018"},{"issue":"2","key":"e_1_2_9_15_1","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCEP.120.009261","article-title":"Long\u2010Term Safety and Feasibility of Left Bundle Branch Pacing in a Large Single\u2010Center Study","volume":"14","author":"Lan S.","year":"2021","journal-title":"Circulation Arrhythmia and Electrophysiology"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehac445"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.70282","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jce.70282","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.70282","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T14:02:27Z","timestamp":1780495347000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.70282"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,8]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1111\/jce.70282"],"URL":"https:\/\/doi.org\/10.1111\/jce.70282","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,8]]},"assertion":[{"value":"2025-10-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}