{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T12:14:07Z","timestamp":1779106447985,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T00:00:00Z","timestamp":1774396800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T00:00:00Z","timestamp":1774396800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The left atrial posterior wall (LAPW) is often targeted in atrial fibrillation (AF) ablation due to its shared properties with pulmonary veins. However, substrate\u2010guided approaches using structural markers have shown inconsistent results. We investigated posterior wall conduction time (PWCT) as a novel and functional marker of LAPW remodeling in AF patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In our pilot study, 40 patients undergoing first\u2010time AF ablation (20 paroxysmal, 20 persistent AF) were included. AF cycle length (AF CL), PW linear conduction, PW conduction area (PWCA) and PWCT were evaluated on electroanatomical mapping at different pacing CLs. Major decremental PWCT was defined as PWCT increase \u2265\u200917% at 400\u2009ms compared to 600\u2009ms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Persistent AF patients had a larger posterior wall area (PWA; 20.4\u2009\u00b1\u20095.2 vs. 16.8\u2009\u00b1\u20094.9\u2009cm\u00b2,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.033), greater low voltage area (LVA; 16.5\u2009\u00b1\u200925.8% vs. 6.1\u2009\u00b1\u200919.8%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.044) and shorter left atrial appendage AF CLs (shortest AF CL 146.2\u2009\u00b1\u200936.3 vs. 179.1\u2009\u00b1\u200937.1\u2009ms,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.012) than paroxysmal AF patients. PWCT was numerically longer in persistent AF, with major \u0394PWCT observed exclusively in 6 persistent AF patients. In this subgroup, PWCA was reduced at each 10\u2009ms increment during 400\u2009ms pacing, a finding not observed in non\u2010major \u0394PWCT subgroup. Major \u0394PWCT did not correlate with PWA size, LVA, or AF CL.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>PWCT may represent a novel functional biomarker of LAPW remodeling, independent of structural changes, potentially identifying patients who may benefit from targeted LAPW ablation. Further studies are needed to validate PWCT as a guide for personalized AF ablation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.70320","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T06:01:24Z","timestamp":1774504884000},"page":"980-988","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Left Atrial Posterior Wall Functional Remodeling in Paroxysmal and Persistent Atrial Fibrillation. A Pilot Study"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6399-4282","authenticated-orcid":false,"given":"Michael M.","family":"Malaty","sequence":"first","affiliation":[{"name":"Department of Cardiology John Hunter Hospital Newcastle New South Wales Australia"},{"name":"School of Medicine University of Newcastle Newcastle New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natasha","family":"Trevaskis","sequence":"additional","affiliation":[{"name":"Department of Cardiology John Hunter Hospital Newcastle New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerissa","family":"Govender","sequence":"additional","affiliation":[{"name":"Department of Cardiology John Hunter Hospital Newcastle New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron L.","family":"Sverdlov","sequence":"additional","affiliation":[{"name":"Department of Cardiology John Hunter Hospital Newcastle New South Wales Australia"},{"name":"School of Medicine University of Newcastle Newcastle New South Wales Australia"},{"name":"Hunter Medical Research Institute Newcastle New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bradley R.","family":"Wilsmore","sequence":"additional","affiliation":[{"name":"Department of Cardiology John Hunter Hospital Newcastle New South Wales Australia"},{"name":"School of Medicine University of Newcastle Newcastle New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malcolm","family":"Barlow","sequence":"additional","affiliation":[{"name":"Department of Cardiology John Hunter Hospital Newcastle New South Wales Australia"},{"name":"School of Medicine University of Newcastle Newcastle New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Jackson","sequence":"additional","affiliation":[{"name":"Department of Cardiology John Hunter Hospital Newcastle New South Wales Australia"},{"name":"School of Medicine University of Newcastle Newcastle New South Wales Australia"},{"name":"Hunter Medical Research Institute Newcastle New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gwilym M.","family":"Morris","sequence":"additional","affiliation":[{"name":"Department of Cardiology John Hunter Hospital Newcastle New South Wales Australia"},{"name":"School of Medicine University of Newcastle Newcastle New South Wales Australia"},{"name":"Hunter Medical Research Institute Newcastle New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,25]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1408288"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.23722"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2022.01.003"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/EVIDoa2200141"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2022.03.012"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.8831"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euaa293"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.111.966226"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euaf134"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euac005"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.05.061"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2022.01.019"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehl093"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2023.08.002"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.15420\/aer.2020.19"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2023.07.007"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-015-0133-1"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.113.001251"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2020.08.016"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2022.12.011"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2023.102052"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.120.009288"}],"container-title":["Journal 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