{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T05:54:26Z","timestamp":1781589266044,"version":"3.54.5"},"reference-count":10,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cardiac amyloidosis is commonly associated with cardiac conduction disease. We sought to determine the prevalence of advanced conduction disease requiring a pacemaker in patients with known cardiac amyloidosis to evaluate current screening practices among patients receiving pacemakers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A two\u2010stage analysis was conducted. First, a retrospective chart review was conducted for all patients with known transthyretin cardiac amyloidosis who attended the Cardiac Amyloidosis clinic at the Victorian and Tasmanian Amyloidosis Service (Australia) from 2014 to 2024 to identify those with a pacemaker implantation. Second, all patients who received a pacemaker at the same centre, were reviewed for the presence of cardiac amyloidosis. Demographic and clinical information was collected to identify \u201cred flags\u201d suggestive of cardiac amyloidosis and the patients that underwent screening were identified.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of those patients with known transthyretin cardiac amyloidosis, 82 (39.8%) patients required a pacemaker for conduction disease. Of the 470 patients who had a pacemaker inserted and did not have a pre\u2010existing diagnosis of cardiac amyloidosis, 50 (10.6%) patients had at least 3 red flags for cardiac amyloidosis. However, only five patients (1.1%) were screened for cardiac amyloidosis and four (80% of those screened) were diagnosed with the condition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A significant proportion of patients with transthyretin cardiac amyloidosis had pre\u2010existing pacemakers. However, only a small proportion of patients who required a pacemaker underwent screening, despite the presence of multiple high\u2010risk features.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.70323","type":"journal-article","created":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T04:48:13Z","timestamp":1773982093000},"page":"1372-1375","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Underscreening of Cardiac Amyloidosis in Patients With Pacemakers\u2014A Single Centre Retrospective Audit"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-0777-5561","authenticated-orcid":false,"given":"Peishan","family":"Cai","sequence":"first","affiliation":[{"name":"School of Medicine Deakin University Geelong Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1104-3511","authenticated-orcid":false,"given":"Timothy","family":"Scully","sequence":"additional","affiliation":[{"name":"Department of Cardiology Box Hill Hospital Box Hill Victoria Australia"},{"name":"Eastern Health Clinical School Monash University Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Nogic","sequence":"additional","affiliation":[{"name":"Department of Cardiology Box Hill Hospital Box Hill Victoria Australia"},{"name":"Eastern Health Clinical School Monash University Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kah","family":"Peck","sequence":"additional","affiliation":[{"name":"Department of Cardiology Box Hill Hospital Box Hill Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jithin","family":"Sajeev","sequence":"additional","affiliation":[{"name":"Department of Cardiology Box Hill Hospital Box Hill Victoria Australia"},{"name":"Eastern Health Clinical School Monash University Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,19]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000792"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.2823"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.06.053"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.84.s3.02"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/openhrt-2014-000177"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/openhrt-2024-002606"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ehf2.14645"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehab072"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2022.1781"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2023.05.002"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.70323","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jce.70323","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.70323","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T05:42:13Z","timestamp":1781588533000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.70323"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,19]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1111\/jce.70323"],"URL":"https:\/\/doi.org\/10.1111\/jce.70323","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,19]]},"assertion":[{"value":"2025-11-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}