{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:01:13Z","timestamp":1785423673688,"version":"3.56.0"},"reference-count":21,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T00:00:00Z","timestamp":1777766400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T00:00:00Z","timestamp":1777766400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000764","name":"King's College London","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000764","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002996","name":"Hartstichting","doi-asserted-by":"publisher","award":["03\u2010003\u20102021\u2010T061"],"award-info":[{"award-number":["03\u2010003\u20102021\u2010T061"]}],"id":[{"id":"10.13039\/501100002996","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Accurate identification of arrhythmogenic substrate is essential for successful ventricular tachycardia (VT) ablation, yet existing electrogram\u2010based methods are limited by far\u2010field interference and operator dependence. Dominant frequency (DF) mapping offers a stimulus\u2010independent alternative, but existing implementations lack anatomically integrated workflows with quantitative assessment of spatial concordance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The objective of this study is to develop and evaluate a computational workflow for DF mapping with three\u2010dimensional anatomical integration in patients undergoing substrate\u2010guided VT ablation. We retrospectively analyzed 12 patients (mean age 57.5\u2009\u00b1\u200918.0 years; 75% male) with ischemic or non\u2010ischemic cardiomyopathy. Intracardiac electrograms from SmartTouch or Pentaray catheters were segmented, transformed into the frequency domain, and thresholded using case\u2010specific histograms. DF activity was projected onto patient\u2010specific ventricular meshes, and spatial correspondence with operator\u2010defined ablation sites was quantified using continuous proximity metrics (soft recall, soft precision) and receiver operating characteristic (ROC) analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>DF analysis was successful in all cases, with projection errors &lt;\u20094\u2009mm. DF activity showed high soft recall (0.776\u20130.999) and variable soft precision (0.025\u20130.754). ROC AUC values ranged from 0.622 to 0.953, exceeding baseline in all cases. SmartTouch data generally yielded higher recall and greater separation between ablation and non\u2010ablation points.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>DF mapping with anatomical integration is feasible across catheter types and demonstrates consistent spatial concordance with operator\u2010defined VT ablation targets. This stimulus\u2010independent workflow can be applied to routine mapping data and provides a framework for quantitative assessment of spatial relationships with procedural targets. DF values were case\u2010specific and not comparable across patients, catheter types, or institutions. Prospective evaluation in larger cohorts is warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.70356","type":"journal-article","created":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T21:05:10Z","timestamp":1777842310000},"page":"1399-1409","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dominant Frequency Mapping as a Functional Tool for Substrate\u2010Guided Ventricular Tachycardia Ablation"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-1431-1907","authenticated-orcid":false,"given":"Selim M.","family":"Zor","sequence":"first","affiliation":[{"name":"Department of Cardiology Amsterdam University Medical Center Amsterdam the Netherlands"},{"name":"Biomedical Engineering Amsterdam University of Applied Sciences Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wiert","family":"Hoeksema","sequence":"additional","affiliation":[{"name":"Department of Cardiology Amsterdam University Medical Center Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart","family":"Baselmans","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Amsterdam University of Applied Sciences Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michiel J. B.","family":"Kemme","sequence":"additional","affiliation":[{"name":"Department of Cardiology Amsterdam University Medical Center Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pieter G.","family":"Postema","sequence":"additional","affiliation":[{"name":"Department of Cardiology Amsterdam University Medical Center Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pranav","family":"Bhagirath","sequence":"additional","affiliation":[{"name":"Department of Cardiology Amsterdam University Medical Center Amsterdam the Netherlands"},{"name":"School of Biomedical Engineering and Imaging Sciences King's College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.repc.2024.04.002"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2021.02.007"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2017.12.005"},{"issue":"2","key":"e_1_2_9_5_1","article-title":"Evoked Delayed Potential Ablation for Post\u2010Myocardial Infarction Ventricular Tachycardia: Results From a Large Prospective Multicentre Study","volume":"27","author":"Riva M.","year":"2025","journal-title":"Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology: Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2023.12.009"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2025.02.034"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13723"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euae253"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2019.06.002"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.15420\/aer.2024.39"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcdd9090288"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.15420\/aer.2020.28"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euad092"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-025-02066-z"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euae114"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euae154"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.19102\/icrm.2019.100302.eCollection2019Mar"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hroo.2022.10.013"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-08743-7"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2022.11.019"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2020.03.003"}],"container-title":["Journal of Cardiovascular Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.70356","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jce.70356","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jce.70356","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T14:06:42Z","timestamp":1785420402000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jce.70356"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,3]]},"references-count":21,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1111\/jce.70356"],"URL":"https:\/\/doi.org\/10.1111\/jce.70356","archive":["Portico"],"relation":{},"ISSN":["1045-3873","1540-8167"],"issn-type":[{"value":"1045-3873","type":"print"},{"value":"1540-8167","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,3]]},"assertion":[{"value":"2025-11-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}