{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T19:14:57Z","timestamp":1791054897830,"version":"4.1.0"},"reference-count":39,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T00:00:00Z","timestamp":1778803200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T00:00:00Z","timestamp":1778803200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cardiovasc electrophysiol"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Arrhythmia\u2010induced cardiomyopathy (AIC) is a potentially reversible cause of heart failure triggered by different sustained arrhythmias, but data on its real\u2010world prevalence, recognition, and outcomes are limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess frequency, predictors, and outcomes of AIC in patients with newly diagnosed left ventricular systolic dysfunction (LVSD) and concurrent arrhythmia undergoing early rhythm control with a wearable cardioverter\u2010defibrillator (WCD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Among 780 WCD\u2010treated patients (2017\u20132023), those with newly diagnosed idiopathic LVSD (LVEF\u2009&lt;\u200935%) and persistent arrhythmia (atrial fibrillation\/flutter or &gt;\u200920% ventricular ectopy) were included. Diagnostic workup comprised echocardiography, coronary angiography, and cardiac MRI. Effective rhythm control was achieved via cardioversion, antiarrhythmic drugs, and\/or ablation. Follow\u2010up was up to 6 months. AIC was defined as LVEF improvement &gt;\u200915% with restored sinus rhythm or suppressed ventricular ectopy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 780 WCD patients, 142 (18.2%) had LVSD with arrhythmia; 74 idiopathic cases were analyzed. At a mean follow\u2010up of 138 days (4.5 months), 54 patients (73%) maintained sinus rhythm or suppressed ventricular ectopy after rhythm control, of whom 32 (59.3%) fulfilled AIC criteria. LVEF improved from 28% to 43% in AIC; 56.3% of AIC patients fully recovered (&gt;\u200950%). Non\u2010AIC patients had larger LV dimensions, lower heart rates, more mitral regurgitation, and a non\u2010significant trend toward more frequent late gadolinium enhancement (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.073). No parameter reliably predicted AIC; LVEF\u2009&lt;\u200925% predicted lack of full recovery (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.040). No appropriate WCD shocks occurred. ICD indication decreased from 100% to 17% post\u2010therapy in AIC and Non\u2010AIC patients (3.1% vs\n                      <jats:italic>.<\/jats:italic>\n                      36.4%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>AIC related to atrial fibrillation, flutter, or frequent ventricular ectopy is more prevalent and reversible than often recognized. Early rhythm control under WCD protection, supported by comprehensive diagnostics, allows identification of reversible LVSD and may help prevent unnecessary ICD implantation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jce.70366","type":"journal-article","created":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T12:51:09Z","timestamp":1778849469000},"page":"1465-1475","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Prevalence and Recovery of Arrhythmia\u2010Induced Cardiomyopathy in Patients With Newly Diagnosed Heart Failure Using a Wearable Defibrillator: A Real\u2010World Cohort Study"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-4042-8331","authenticated-orcid":false,"given":"Joerg","family":"Yogarajah","sequence":"first","affiliation":[{"name":"Department of Cardiology, Kerckhoff Heart and Thorax Center, Campus Kerckhoff Justus Liebig University Giessen Bad Nauheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Dannebaum","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Kerckhoff Heart and Thorax Center, Campus Kerckhoff Justus Liebig University Giessen Bad Nauheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Halim","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Kerckhoff Heart and Thorax Center, Campus Kerckhoff Justus Liebig University Giessen Bad Nauheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamschid","family":"Sedighi","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Medical Clinic I Justus Liebig University Giessen Giessen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Mensch","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Kerckhoff Heart and Thorax Center, Campus Kerckhoff Justus Liebig University Giessen Bad Nauheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malte","family":"Kuniss","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Kerckhoff Heart and Thorax Center, Campus Kerckhoff Justus Liebig University Giessen Bad Nauheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Neumann","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Kerckhoff Heart and Thorax Center, Campus Kerckhoff Justus Liebig University Giessen Bad Nauheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Rieth","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Kerckhoff Heart and Thorax Center, Campus Kerckhoff Justus Liebig University Giessen Bad Nauheim 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